Mycopathologia et mycologia applicata

, Volume 39, Issue 2, pp 113–120 | Cite as

Serological and skin test cross-reactivity between Histoplasma capsulatum and Oidiodendron kalrai

  • R. P. Tewari
  • C. R. Macpherson
  • T. K. Maitra
Article

Abstract

Guinea pigs were infected with yeast cells ofHistoplasma capsulatum andOidiodendrom kalrai. They were skin tested 6 and 12 weeks post-infection with both homologous and heterologous antigens. There was almost complete skin test cross-reactivity between histoplasmin and oidiodendrin after 12 but not after 6 weeks. There were also strong serologic cross-reactions among 6 different anti-H. capsulatum hyperimmune sera and oidiodendrin. However, cross-reactions among anti-O. kalrai sera and histoplasmin could not be demonstrated.

Keywords

Yeast Cell Skin Test Starke Heterologous Antigen Hyperimmune Seron 

Zusammenfassung

Meerschweinchen sind mit Hefezellen vonHistoplasma capsulatum undOidiodendron kalrai infiziert worden. Sie waren nach 6 und 12 Wochen mit homologen und heterologen Antigenen Haut-tested. Es war eine fast völlige Hauttest-Kreuzreaktion zwischen Histoplasmin und Oidiodendrin nach 12 aber nicht nach 6 Wochen. Es gab auch eine starke, serologische Kreuzreaktion unter sechs verschiedenen Anti-H. capsulatum Hyperimmunsera und Oidiodendrin. Jedoch konnte man Kreuzreaktionen unter Anti-O. kalrai Sera und Histoplasmin nicht feststellen.

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Copyright information

© Dr. W. Junk N.V. 1969

Authors and Affiliations

  • R. P. Tewari
    • 1
  • C. R. Macpherson
    • 1
  • T. K. Maitra
    • 1
  1. 1.Departments of Microbiology and PathologyOhio State University, College of MedicineColumbus

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