Abstract
The genetic effects of acriflavine have been studied on two different strains ofFusarium with regard to photodynamic inactivation and reversion of genetic markers. The survival curves of R79 strain ofFusarium redolens are nearly exponential, whereas those of an interspecific recombinant betweenF. redolens andF. oxysporum have a broad shoulder. In the presence of acriflavine photodynamic inactivation was observed that did not result in a change in the shapes of the survival curves. In the presence of acriflavine photodynamic induced reversion of the genetic markers in each strain was also observed.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Avers, C. J., Pfeffer, R. C. &Rancourt, M. W. (1955b) Acriflavine induction of different kinds of petite mitochondrial population inSaccharomyces cerevisiae.J. Bact. 90:481–494.
Brenner, S., Barnett, L., Crick, F. H. C. &Orgel, A. (1961) The theory of mutagenesis.J. Mol. Biol. 3:121–124.
Buxton, E. W. &Hastie, A. C. (1962) Spontaneous and ultra-violet irradiation induced mutants ofVerticillium albo-atrum.J. Gen. Microbiol. 28:625–632.
Crick, F. H.-C., Barnett, L., Brenner, S. &Watts-Tobin, R. J. (1961) General nature of the genetic code for proteins.Nature 192:1227.
Hayes, W. (1965) The genetics of bacteria and their viruses. Blackwell Scientific Publications, Oxford, 740 pp.
Lerman, L. S. (1963) The structure of the DNA-acridine complex.Proc. Natl. Acad. Sci. (U.S.A.) 49:94–102.
Nagai, S. (1959) Induction of the respiration deficient mutation in yeast by various synthetic dyes.Science 130:1188–1189.
Nagai, S. &Nagai, H. (1958) A new evidence for induction of respiration deficiency in yeast by acriflavine.Experientia 14:321–323.
Orgel, A. &Brenner, S. (1961) Mutagenesis of bacteriophages T4 by acridines.J. Mol. Biol. 3:762–768.
Ritchie, D. A. (1964) Mutagenesis with light and proflavine in phage T4.Genet. Res. 5:168–169.
Ryan, F. J. &Kiritani, K. (1959) Effect of temperature on natural mutation inEscherichia coli.J. gen. Microbiol. 20:644–653.
Sarabhai, A. &Lamfrom, H. (1969) Mechanism of proflavine mutagenesis.Proc. Natl. Acad. Sci. (U.S.A.) 63:1196–1197.
Sidiqui, O. H. (1962) Mutagene action of nitrous acid onAspergillus nidulans.Genet. Res. 3:303–314.
Singh, H. N. (1968) Effect of acriflavine on ultra-violet sensitivity of normal, ultra-violet sensitive and ultra-violet resistant strains of a blue-green alga,Anacystis nidulans.Radiation Bot. 8:355–361.
Singh, U. P. (1970) Photodynamic inactivation and reversion inFusarium species with acriflavine.Experientia 26:547.
Singh, U. P. &Hoffmann, G. M. (1969) Synthesis of heterokaryons and parasexual reaction inFisarium species.Arch. Mikrobiol. 67:293–305.
Wagner, R. P. &Mitchell, H. K. (1955) Genetics and metabolism. New York, John Wiley and Sons Inc.
Webb, R. B. &Kubitschek, H. E. (1963) Mutagenic and antimutagenic effect of acridine orange inE. coli.Bioch. Biophys. Res. Commun. 13:90–94.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Singh, U.P. Effect of acriflavine on UV-induced mutants of Fusarium species. Mycopathologia et Mycologia Applicata 50, 183–193 (1973). https://doi.org/10.1007/BF02053367
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF02053367