Summary
The impact of guanidine hydrochloride on the utilization and synthesis of oligosaccharides by pathogenicFusaria from sucrose solution, was studied employing chromatographic technique. The results are significant, in that, they show that the site of action is remote from the enzyme β-fructosidase which is not disrupted by this chemical into its component units — the isozymes, and the chemical signal is interpreted by the operon governing the enzyme synthesis. The possibility of the enzyme β-fructosidase undergoing an allosteric transition with modification of its active site is also discussed in the light of experimental results.
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Kakkar, R.K. Studies on metabolic inhibitors I. Guanidine hydrochloride and utilization of sucrose by pathogenic Fusaria. Mycopathologia et Mycologia Applicata 37, 281–288 (1969). https://doi.org/10.1007/BF02051362
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DOI: https://doi.org/10.1007/BF02051362