Skip to main content

Advertisement

Log in

Surgical management of nonhepatic intra-abdominal recurrence of carcinoma of the colon

  • Original Contributions
  • Published:
Diseases of the Colon & Rectum

Abstract

The role of surgery in the management of intra-abdominal recurrence of colon cancer has not been clearly determined. We reviewed the charts of 28 patients operated upon at our institution for nonhepatic intra-abdominal recurrence of carcinoma of the colon and followed for a median of 10.5 months after reoperation. Total resection of gross disease was possible in 15 patients, who had a median overall actuarial survival of 25.5 months and a disease-free survival of 13 months. Within this group, disease-free survival was significantly prolonged when time to first recurrence was greater than 16 months and when patients had not had a prior operation for recurrent disease (P<0.05). Six patients having a partial resection and seven patients having only a bypass or ostomy had significantly shorter survivals than those in the totally resected group, with median survivals of 8 and 3.5 months, respectively (P<0.05). Operative management of recurrent colon cancer may prolong survival when disease can be eradicated, and palliative operations appear more successful when tumor is resected rather than bypassed.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Itwatsuki S, Starzl TE. Personal experience with 411 hepatic resections. Ann Surg 1988;208:421–34.

    Article  PubMed  Google Scholar 

  2. Hughes KS, Simon R, Songhorabodi S,et al. Resection of the liver for colorectal metastases: a multiinstitutional study of indications for resection. Surgery 1988;103:278–88.

    PubMed  Google Scholar 

  3. Willen CG, Tepper JE, Cohen AM, Orlow E, Welch CE. Failure patterns following curative resection of colonic carcinoma. Ann Surg 1984;200:685–90.

    PubMed  Google Scholar 

  4. Boring CC, Squires TS, Tong T. Cancer statistics, 1992. CA 1992;42:19–38.

    Article  PubMed  CAS  Google Scholar 

  5. Lee ET, Desu MM. A computer program for comparing k samples with right-censored data. Comput Methods Programs Biomed 1972;2:315–21.

    Article  CAS  Google Scholar 

  6. Gunderson LL, Sosin H. Areas of failure found at reoperation (second or symptomatic look) following “curative surgery” for adenocarcinoma of the rectum: clinicopathologic correlation and implications for adjuvant therapy. Cancer 1974;34:1278–92.

    PubMed  CAS  Google Scholar 

  7. Vassilopoulos PP, Yoon JM, Ledesma EJ, Mittelman A. Treatment of recurrence of adenocarcinoma of the colon and rectum at the anastomotic site. Surg Gynecol Obstet 1981;152:777–80.

    PubMed  CAS  Google Scholar 

  8. Stulc JP, Petrelli NJ, Herrera L, Mittelman A. Anastomotic recurrence of adenocarcinoma of the colon. Arch Surg 1986;121:1077–80.

    PubMed  CAS  Google Scholar 

  9. Pihl E, Hughes ES, McDermott FT, Price A. Recurrence of carcinoma of the colon and rectum at the anastomotic suture line. Surg Gynecol Obstet 1981;153:495–6.

    PubMed  CAS  Google Scholar 

  10. Schiessel R, Wunderlich M, Herbst F. Local recurrence of colorectal cancer: effect of early detection and aggressive surgery. Br J Surg 1986;73:342–4.

    PubMed  CAS  Google Scholar 

  11. Makela J, Haukipuro K, Laitinen S, Kairaluoma MI. Surgical treatment of recurrent colorectal cancer. Arch Surg 1989;124:1029–32.

    PubMed  CAS  Google Scholar 

  12. Stipa S, Nicolanti S, Botti C,et al. Local recurrence after curative resection for colorectal cancer: frequency, risk factors and treatment. J Surg Oncol 1991;2(Suppl):155–60.

    CAS  Google Scholar 

  13. Benotti PN, Bothe A Jr, Eyre RC, Cady B, McDermott WV, Steele G. Management of recurrent pelvic tumors. Arch Surg 1987;122:457–60.

    PubMed  CAS  Google Scholar 

  14. Quentmeier A, Schlag P, Smok M, Herfarth C. Reoperation for recurrent colorectal cancer: the importance of early diagnosis for resectability and survival. Eur J Surg Oncol 1990;16:319–25.

    PubMed  CAS  Google Scholar 

  15. Waldron RP, Donovan IA. Clinical follow-up and treatment of locally recurrent colorectal cancer. Dis Colon Rectum 1987;30:428–30.

    PubMed  CAS  Google Scholar 

  16. Minton JP, Hoehn JL, Gerber DM,et al. Results of a 400-patient carcinoembryonic antigen second-look colorectal cancer study. Cancer 1985;55:1284–90.

    PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Additional information

Supported in part by an American Cancer Society Clinical Oncology Fellowship Award (Dr. Gwin).

About this article

Cite this article

Gwin, J.L., Hoffman, J.P. & Eisenberg, B.L. Surgical management of nonhepatic intra-abdominal recurrence of carcinoma of the colon. Dis Colon Rectum 36, 540–544 (1993). https://doi.org/10.1007/BF02049858

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02049858

Key words

Navigation