Journal of Radioanalytical and Nuclear Chemistry

, Volume 114, Issue 1, pp 195–202 | Cite as

The importance of the geometrical factor in nuclear activation analysis

  • G. E. Nicolaou
  • N. M. Spyrou
  • Y. S. Khrbish
In Vivo Analysis


When a beam of radiation is used as a probe in order to study the elemental composition of an object, the factors involved in obtaining maximum detection sensitivity include target homogeneity, beam uniformity and the solid angle subtended between target and detector. Here we have investigated, both theoretically and experimentally, the significance of these factors in an experimental facility for ‘in-vitro’ prompt gamma-ray neutron activation analysis and an arrangement used in ‘in-vivo’ activation analysis. The correction factor to the solid angle, to account for non-uniformity, and the optimisation of reaction rate and solid angle are considered.


Radiation Physical Chemistry Inorganic Chemistry Correction Factor Activation Analysis 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    K. HEYDORN, Neutron Activation Analysis for Clinical Trace Element Research, Vol. 1, CRC Press, Florida, USA, 1984.Google Scholar
  2. 2.
    D. M. ALBURY, N. M. SPYROU, Nucl. Instr. Methods, A242 (1986) 635.Google Scholar
  3. 3.
    L. WIELOPOLSKI, Nucl. Instr. Methods, 143 (1977) 577.Google Scholar
  4. 4.
    Y. S. KHRBISH, N. M. SPYROU, Geometrical Factor in Absolute Measurements Using Prompt Gamma-ray Activation Analysis, The International Conference on Analytical Chemistry in Nuclear Technology, Karlsruhe, FRG, 1985.Google Scholar
  5. 5.
    N. M. SPYROU, I. P. MATTHEWS, J. Radioanal. Chem., 61 (1981) 195.Google Scholar
  6. 6.
    G. E. NICOLAOU, I. P. MATTHEWS, L. G. STEPHENS-Newsham, N. M. SPYROU, J. Radioanal. Chem., 71 (1982) 519.Google Scholar
  7. 7.
    J. B. KRANEL, M. A. SPEED, B. N. THOMAS, H. BUDDELEY, B. J. THOMAS, Int. J. Appl. Radiation, Isotopes, 31 (1980) 101.Google Scholar
  8. 8.
    G. E. NICOLAOU, Ph. D. Thesis (Physics), University of Surrey, UK, 1983.Google Scholar

Copyright information

© Akadémiai Kiadó 1987

Authors and Affiliations

  • G. E. Nicolaou
    • 1
  • N. M. Spyrou
    • 1
  • Y. S. Khrbish
    • 1
  1. 1.Department of PhysicsUniversity of SurreyGuildford(UK)

Personalised recommendations