Summary
Blood-pressure depressing non-dialysable substances of urine are precipitable by Uranylacetat and are eluted by Diammoniumphosphat. A following separation by elektrophoresis shows two fractions, that are depressing blood-pressure. One of these is the thermounstable Kallikrein, the other the thermostable Depressan.
Similar content being viewed by others
Literatur
Bauer, A.: Naunyn-Schmiedeberg's Arch. exp. Path. Pharmak.168, 111 (1932).
Fischer, F. G., u.H. Dörfel: Biochem. Z.324, 544 (1953).
Frey, E. K., H. Kraut u.E. Werle: Kallikrein. Stuttgart: Enke 1950.
Grassmann, W., u.K. Hannig: Z. physiol. Chem.292, 32 (1953).
Green, H. D., J. M. Little, J. Hester andH. Hildermann: Fed. Proc.6, 114 (1947).
Green, H. D., J. M. Little, C. G. Gaddy, L.T. Franklin andH. H. Wayne: Circulation5, 567 (1952).
Grollman, A., J. R. Williams jr. andT. R. Harrison: J. Amer. med. Ass.115, 1169 (1940).
Little, J. M., H. D. Green andJ. I. Baumgarner: Amer. J. Physiol.155, 345 (1948).
Moeller, J., u.K. Schöfling: Z. klin. Med.146, 273 (1950).
Sarnoff, S. J., R. B. Case, R. Macruz, K. E. Susman andJ. V. Pierce: Circulat. Res.6, 522 (1958).
Weese, H.: Naunyn-Schmiedeberg's Arch. exp. Path. Pharmak.173, 36 (1933).
Wieland, Th., u.G. Pfleiderer: Ang. Chem.67, 257 (1955).
Wollheim, E.: Schweiz. med. Wschr.66, 1231 (1936).
—: Acta med. scand.91, 1 (1937).
—: Acta physiol. scand.10, 126 (1945).
—: Z. klin. Med.145, 61 (1949).
Wollheim, E., u.K. Lange: Dtsch. med. Wschr.58, 572 (1932).
Author information
Authors and Affiliations
Additional information
Herrn Professor Dr. H.Netter zum 60. Geburtstag.
Herrn Professor Dr. F. G. Fischer möchte ich ganz besonders für die Unterstützung bei der Durchführung dieser Arbeit danken.
Rights and permissions
About this article
Cite this article
Gross, W. Trennung der thermolabilen und der thermostabilen gefäßerweiternden Substanzen aus Harn. Z. Gesamte Exp. Med. 132, 93–101 (1959). https://doi.org/10.1007/BF02048815
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF02048815