Skip to main content
SpringerLink
Log in

A study using neutron activation analysis of the short-term changes in the selenium content of blood components in human following supplementation with low doses of selenium

  • Published:
Journal of Radioanalytical and Nuclear Chemistry Aims and scope Submit manuscript

Abstract

A study was undertaken to evaluate the short-term changes in the concentration of selenium in whole blood, plasma and erythrocytes following supplementation with low doses of four different selenium supplements. Fourteen volunteers took one of the supplements each day with breakfast for a period of six weeks. Two blood samples were taken each week during this time and selenium was determined on its components using neutron activation analysis via the77mSe isotope.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. W. MERTZ, Trace elements in nutrition, in: Trace Element Analytical Chemistry in Medicine and Biology, P. BRATTER and P. SCHRAMEL (Eds), Walter de Gruyter, Berlin, 1980, p. 727.

    Google Scholar 

  2. G. V. IYENGAR, Concentration of 15 trace elements in some selected adult human tissues and body fluids of clinical interest from several countries: Results from a pilot study for the establishment of reference values, JUL-1974, 1985, p. 114.

  3. G. ALFTHAN, A. ARO, J. K. HUTTUNEN, Supplementation of a population with selenium—Reasons for action and initial experience, in: Selenium in Biology and Medicine, A. WENDEL (Ed.), Springer-Verlag Publishing, Tubingen, FRG, 1988, p. 210.

    Google Scholar 

  4. M. F. ROBINSON, H. M. REA, G. M. FRIEND, R. D. H. STEWART, P. C. SNOW, C. D. THOMSON, Br., J. Nutr., 39 (1978) 589.

    Google Scholar 

  5. G. YANG, L. GU, R. ZHOU, S. YIN, Studies of human maximal and minimal safe intake and requirement of selenium, in: Selenium in Biology and Medicine, A. WENDEL (Ed.), Springer-Verlag Publishing, Tubingen, FRG, 1988, p. 222.

    Google Scholar 

  6. M. F. ROBINSON, D. R. CAMPBELL, D. H. STEWART, H. M. REA, C. D. THOMSON, P. G. SNOW, I. H. W. SQUIRES, NZ Med. J., 93 (1981) 289.

    Google Scholar 

  7. A. A. DAMYANOVA, O. B. AKANLE, N. M. SPYROU, J. Radioanal. Nucl. Chem., 113 (1987) 431.

    Google Scholar 

  8. G. C. GUIDI, G. BELLISOLA, R. SCHIAVON, S. GALASSINI, N. Q. LIU, G. MOSCHINI, Effects of increasing dietary selenium intake in humans: preliminary results of a longitudinal study, in: Trace Element Analytical Chemistry in Medicine and Biology, P. BRATTER, P. SCHRAMEL (Eds.) Walter de Gruyter, Berlin, 1988, p. 377.

    Google Scholar 

  9. J. CLAUSEN, S. A. NIELSEN, Comparison of whole blood selenium values and erythrocyte glutathione peroxidase activities of normal individuals on supplementation with selenate, selenite, L-selenomethionine and high selenium yeast, in: Selenium-Present status and perspectives in biology and medicine, G. N. SCHRAUZER (Ed.), Humana Press Publishing, Nonnweiler, West Germany, 1988, p. 125.

    Google Scholar 

  10. M. F. ROBINSON, C. D. THOMPSON, Selenium levels in humans vs environmental sources, in: Selenium in Biology and Medicine. J. E. SPALLHOLZ, J. L. MARTIN, H. E. GANTHER (Eds): AVI Publishing, Westport, Connecticut, 1981, p. 283.

    Google Scholar 

  11. M. F. ROBINSON, Clinical effects of selenium deficiency and excess, in: Clinical, Biochemical, and Nutritional Aspects of Trace Elements. A. R. LISS (Ed.) New York, 1982, p. 325.

  12. O. A. LEVANDER, G. ALFTHAN, H. ARVILOMMI, C. G. GREF, J. K. HUTTUNEN, M. KATAJA, P. KOIVISTOINEN, J. PIKKARAINEN, Am. J. Clin. Nutr., 37 (1983) 887.

    PubMed  Google Scholar 

  13. G. ALFTHAN, A. ARO, H. ARVILOMMI, J. K. HUTTUNEN, Am. J. Clin. Nutr., 53 (1991) 120.

    PubMed  Google Scholar 

  14. E. JOHANSSON, L. O. PLATIN, V. GALGAN, T. WESTERMARCK, U. R. NORDBERG, Comparison of human response to low doses of inorganic and organic selenium, in: Selenium in Biology and Medicine, A. WENDEL (Ed.), Springer-Verlag Publishing, Tubingen, FRG, 1988, p. 258.

    Google Scholar 

  15. J. J. FARDY, G. D. McORIST, Y. J. FARRAR, J. Radioanal. Nucl. Chem., 133 (1989) 397.

    Google Scholar 

  16. G. D. McORIST, J. J. FARDY, T. M. FLORENCE, J. Radioanal. Nucl. Chem., 119 (1987) 449.

    Google Scholar 

  17. G. D. McORIST, J. J. FARDY, (in print).

Download references

Author information

Authors and Affiliations

  1. ANSTO Industrial Technology Program, Lucas Heights Research Laboratories, Private Mail Bag 1, Menai, NSW, (Australia)

    G. D. McOrist & J. J. Fardy

  2. Department of Chemistry, University of Technology, Sydney, P.O. Box 123, Broadway, NSW, (Australia)

    R. Sleet

Authors
  1. G. D. McOrist
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. J. J. Fardy
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. R. Sleet
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

McOrist, G.D., Fardy, J.J. & Sleet, R. A study using neutron activation analysis of the short-term changes in the selenium content of blood components in human following supplementation with low doses of selenium. Journal of Radioanalytical and Nuclear Chemistry, Articles 158, 293–301 (1992). https://doi.org/10.1007/BF02047116

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02047116

Keywords

Search

Navigation