Antonie van Leeuwenhoek

, Volume 33, Issue 1, pp 213–219 | Cite as

Failure to detect interfering agents in febrile respiratory illnesses

  • J. H. E. Custers
  • J. van der Veen


Throat swab specimens from 57 military recruits with febrile respiratory illness in whom no virologic or serologic evidence of infection with respiratory viruses orMycoplasma pneumoniae was found were inoculated and passaged into fresh cultures of monkey kidney cells and continuous lines of human, simian and rabbit cells. Cultures of second passage were challenged with poliovirus type 2 or vaccinia virus and subsequently tested for interference by reading of cytopathic effect and titration of challenge virus. No interference was shown.


Respiratory Illness Vaccinia Virus Kidney Cell Continuous Line Vaccinia 
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Copyright information

© Swets & Zeitlinger 1967

Authors and Affiliations

  • J. H. E. Custers
    • 1
  • J. van der Veen
    • 1
  1. 1.Department of HygieneUniversity of NijmegenNijmegenThe Netherlands

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