Zusammenfassung
Mit dem periodischen Absaugen des Magensaftes nach Pylorusligatur kann man bei Ratten eine schwere Exsiccose erreichen. Zur Erzielung einer experimentellen Exsiccose scheint diese Methode an Ratten geeigneter als die bisher beschriebenen.
Summary
When the pylorus is ligated and gastric juice periodically aspirated a severe exsiccosis of the salt-deficiency type is produced. It would appear that this method of producing dehydration is superior to older ones.
Literatur
Gamble, J. L., S. G. Ross, andN. Tisdall: The metabolism of fixed base during fasting. J. biol. Chem.57, 633 (1923).
—, andM. A. McIver: Body fluid changes due to continued loss of the external secretion of the pancreas. J. exp. Med.48, 859 (1929).
— —: A study of the effect of pyloric obstruction in rabbits. J. clin. Invest.1, 531 (1925).
Gömöri, P., andP. Marsovszky: Organic acidosis in hypochloremic azotemia after pyloric obstruction. Acta med. scand.93, 42 (1937).
- I.Juhász, M.Roger, and L.Takácsy-Nagy: Orv. Hetil. (im Druck).
Kerpel-Fronius, E.: Durstexsiccose und Salzmangelexsiccose. Acta paediat.22, 143 (1937).
—: Pathologie und Klinik des Salz- und Wasserhaushaltes. Budapest: Verl. d. ung. Akad. 1959.
Lewis, A. C., M. E. Rubini, andW. R. Beisel: A method for rapid dehydration of rats. J. appl. Physiol.15, 525 (1960).
Marriott, W. McKim: Anhydremia. Physiol. Rev.3, 275 (1923), zit. in7.
Roger, M. M.: Circulatory changes in dehydration. Acta med. Acad. Sci. hung. (im Druck).
Sapirstein, L. A.: Regional blood flow by fractional distribution of indicators. Amer. J. Physiol.193, 161 (1958).
Sellers, A. L.: The mechanism and significance of protein excretion by the normal kidney. Arch. intern. Med.6, 801 (1956).
Shay, H., S. A. Komarow, S. S. Fels, D. Meranze, M. Gruenstein, andH. Siplet: A simple method for the uniform production of gastric ulceration in the rat. Gastroenterology5, 43 (1945).
Takács, L., u.K. Kállay: Angaben zur Veränderung der Nierenzirkulation in Exsiccosis. Magy. belorv. Arch.2, 71 (1957).
Talma, S.: Untersuchungen über Ulcus ventriculi simplex, Gastromalazie und Ileus. Z. klin. Med.17, 10 (1890).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Roger, M.M. Exsiccose bei Ratten. Z. Gesamte Exp. Med. 139, 139–143 (1965). https://doi.org/10.1007/BF02043931
Received:
Published:
Issue Date:
DOI: https://doi.org/10.1007/BF02043931