Abstract
Brainstem auditory evoked potentials (BAEPs) have been investigated in 34 patients affected by Multiple Sclerosis. Abnormalities were found in 68% of the patients. Silent lesions of the brainstem were detected in 60% of the clinically definite and in 44% of the probable cases. The diagnostic value of these findings is discussed.
Sommario
I potenziali evocati uditivi sono stati investigati in 34 pazienti affetti da sclerosi multipla. Anormalità sono state evidenziate nel 68% dei pazienti affetti da sclerosi multipla clinicamente definita. Lesioni silenti del brainstem sono state trovate nel 60% delle forme clinicamente definite e nel 44% di quelle probabili. Il valore diagnostico di questi reperti è discusso.
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References
Brown F.R., Shimizu H., McDonald J.M., Moser A.B., Marquis P., Chen W.W., Moser H.W.Auditory evoked brainstem responses and high performance liquid chromatography sulfatide assay as early indices of metachromatic leukodystrophy. Neurology, 31; 980–985, 1981
Buchwald J.J., Huang C.M.Far-field acoustic response: origins in the cat. Science 189: 382–384, 1975
Chiappa K.H., Harrison J.L., Brooks E.B., Young R.R.Brainstem auditory evoked responses in 200 patients with multiple sclerosis. Ann. Neurol., 7: 135–143, 1980.
Chiappa K.H.Pattern shift visual, brainstem auditory and short-latency somatosensory evoked potentials in multiple sclerosis. Neurology, 30: 110–123, 1981.
Chiappa K.H., Ropper A.H.Evoked potentials in clinical medicine. N. Engl. J. Med. 306: 1140–1150, 1982.
Fujita M., Hosoki M., Miyazaki M.Brainstem auditory evoked responses in spinocerebellar degeneration and Wilson disease. Ann. Neurol. 9: 42–47, 1981.
Karnase D.S., Marshall L.F., McCarthy C.S., Klauber M.R., Bickford R.G.Localizing and prognostic value of auditory evoked responses in coma after closed head injury. Neurology 32 (3) 299–302, 1982
Khoshbin S., Hallett M.Multimodality evoked potentials and blink reflex in multiple sclerosis. Neurology 31: 138–144, 1981
Kjaer M.Variations of brainstem auditoryevoked potentials correlated to duration and severity of multiple sclerosis. Acta Neurol. Scand. 61: 157–166, 1980.
Lehtinen I., Frey H.Neurophvsiological diagnosis of multiple sclerosis. Acta Neurol. Scand. Suppl. 67, 57: 236–241, 1978
Lev A., Sohmer H.Sources of averaged neural responses recorded in animal and human subjects during cochlear audiometry. Arch. Klin. Exp. Ohr-Nas-Kehlkheilk 201: 79–90, 1972
McDonald W.I., Halliday A.M.Diagnosis and classification of multiple sclerosis. Brit. Med. Bull. 33: 4–8, 1977
Maurer K., Schafer E., Hopf H.C., Leitne H.The location by early auditory evoked potentials of acoustic nerve and brainstem demyelination in multiple sclerosis. J. Neurol. 223: 45–58, 1980
Ochs R., Markand O.N., De Myer W.E.Brainstem auditory evoked responses in leukodystrophies. Neurology 29: 1089–1093, 1979.
Parker S.W., Chiappa K.H., Brooks E.B.Brainstem auditory evoked responses in patients with acoustic neuromas and cerebellar-pontine angle meningiomas. Neurology 30: 413–414, 1980.
Parving A., Elberling G., Smith T.Auditory electrophysiology: findings in multiple sclerosis. Audiology, 20: 123–142, 1981
Picton T.W., Hillyard S.A., Krausz H.I., Galambos R.,Human Auditory evoked potentials: evaluation of components. Electroenc. Clin. Neurophysiol. 36: 179–190, 1974.
Prasher D.K., Gibson W.P.R.Brainstem auditory evoked potentials: a comparative study of monoaural versus binaural stimulation in the detection of multiple sclerosis. Electroenceph. Clin. Neurophysiol., 50: 247–253, 1980.
Robinson K., Rudge P.:Abnormalities of the auditory evoked potentials in patients with multiple sclerosis. Brain 100: 19–40, 1977.
Robinson K., Rudge P.:Tue use of the auditory evoked potential in the diagnosis of multiple sclerosis. J. Neurol. Sci. 45: 235–244, 1980.
Shanon E., Gold S., Himmelfarb M.Z., Carasso R.Auditory potentials of cochlear nerve and brainstem in multiple sclerosis. Arch. Otolaryngol. 105: 505–508, 1979.
Starr A., Achor L.J.Auditory brainstem responses in neurological diseases. Arch. Neurol. 32: 761–768, 1975.
Starr A., Achor L.J.The generators of the auditory brainstem potentials as revealed by brainstem lesions in both cat and man. In: Evoked electrical activity in the auditory nervous system. Ed. R. Nanton and C. Fernandez Acad press NY 1978, 443–452.
Starr A.:Clinical relevance of brainstem auditory evoked potentials in brainstem disorders in man. In: Auditory Evoked Potential in Man. Psychophar. Correlates of evoked potentials. Progress in Clinic. Neurophysiol. Ed. J.E. Desmedt, Karger and Basel 1977, 2, 45–57.
Stockard J., Stockard J., Sharbrough F.W.Detection and localization of occult lesions with brainstem auditory responses. Mayo Clinic Proc. 52: 761–769, 1977.
Soudant J., Frochet B., Frochet M.M., Praloux P., Delaporte P., Salama J.Etude des potentiels évoqués auditifs au cours de la sclérose en plaquer. Rev. Neurol. 135: 895–901, 1979.
Trojaborg W., Bottcher J., Saxtrup O.Evoked potentials and immunoglobulin abnormalities in multiple sclerosis. Neurology 31: 866–871, 1981.
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La Mantia, L., Milanese, C., Corridori, F. et al. Brainstem auditory evoked potentials in the diagnosis of multiple sclerosis. Ital J Neuro Sci 3, 289–293 (1982). https://doi.org/10.1007/BF02043576
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DOI: https://doi.org/10.1007/BF02043576