The Italian Journal of Neurological Sciences

, Volume 3, Issue 4, pp 273–280 | Cite as

Lymphocyte populations in patients with myasthenia gravis. Influence of thymectomy and immunosuppressive drugs

  • Ippoliti G. 
  • Piccolo G. 
  • Lombardi M. 
  • Carnevale Maffé G. 
  • Cosi V. 
  • Pinelli P. 
Original Articles


The T/B peripheral blood lymphocyte ratio was evaluated in 51 patients with myasthenia gravis by means of the rosette test and HTLA. Total T cells and T γ and Tμ.


Myasthenia Gravis T cell B cell Thymectomy Immunosuppressive Drugs 


In 51 pazienti affetti da miastenia gravis sono state valutate, mediante il test delle rosette ed un siero anti-T, le popolazioni linfocitarie T e B. I risultati dimostrano una diminuzione delle cellule T, dei Tγe dei Tμ.

La pregressa timectomia e/o il trattamento immunosoppressivo induce un aumento dei T linfociti HTLA positivi, mentre quelli E rosette positivi permangono a valori inferiori alla norma.

Questo differente comportamento può essere dovuto alla presenza in circolo di linfociti T in differenti stadi di maturazione.


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Copyright information

© Masson Italia Editori S.p.A. 1982

Authors and Affiliations

  • Ippoliti G. 
    • 1
  • Piccolo G. 
    • 2
  • Lombardi M. 
    • 2
  • Carnevale Maffé G. 
    • 1
  • Cosi V. 
    • 2
  • Pinelli P. 
    • 3
  1. 1.Clinica Medica I “A. Ferrata” dell'Università di PaviaItalia
  2. 2.Clinica Neurologica dell'Università di PaviaItalia
  3. 3.Clinica Neurologica I dell'Università di MilanoItalia

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