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Preliminary experience with the 1.32 μm neodymium-YAG laser in the treatment of tracheobronchial malignancy

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Abstract

Endoscopic laser treatment for tracheobronchial malignancy is usually given with the neodymium-YAG laser using the 1.064μm output beam. However, recent experimental work suggests that the 1.32μm output beam of this laser has more desirable tissue effects. We have now treated 55 patients with the 1.32μm Nd-YAG laser (MBB-Medizintechnic) under general anaesthesia, using power settings of 10–20 W and pulse durations of up to 1 s. The indications for treatment were localized airway obstruction in each case. Airway calibre was improved in 46 (84%) patients and this was associated with an improvement in symptoms of cough and breathlessness. Patients with tracheal and carinal obstruction exhibited the most striking clinical improvements with up to four-fold increases in peak expiratory flow. In patients with more peripheral endobronchial obstruction, treatment improved airway calibre less frequently and resulted in a smaller clinical improvement. Of 11 patients with obstruction of a main bronchus and lung collapse, treatment led to partial or complete re-expansion in 10 cases (91%). The 1.32μm wavelength allows treatment to be conducted efficiently and safely but at a considerably lower power than is required for the 1.064μmwavelength. The ability to use low powers has the apparent advantage of generating only negligible quantities of smoke. Our experience with this new laser system demonstrates its considerable potential in the management of tracheobronchial malignancy.

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References

  1. Toty L, Personne C, Colchen A, Vourc'h G. Bronchoscopic management of tracheal lesions using the neodymium-yttrium-aluminium-garnet laser.Thorax 1981,36:175–8

    PubMed  CAS  Google Scholar 

  2. Dumon JF, Reboud E, Garbe L et al. Treatment of tracheo-bronchial lesions by laser photoresection.Chest 1982,81:278–84

    PubMed  CAS  Google Scholar 

  3. McDougall JC, Cortese DA. Neodymium-YAG laser therapy of malignant airway obstruction. A preliminary report.Mayo Clin Proc 1983,58:35–9

    PubMed  CAS  Google Scholar 

  4. Arabian A, Spagnolo SV. Laser therapy in patients with primary lung cancer.Chest 1984,86:519–23

    PubMed  CAS  Google Scholar 

  5. Haussinger K, Held E, Huber R. Endobronchial laser therapy—differential therapeutic use and clinical value.Klin Wochenschr 1984,62:74–80

    Article  PubMed  CAS  Google Scholar 

  6. Parr GVS, Unger M, Trout RG, Atkinson WG. One hundred neodymium-YAG laser ablations of obstructing tracheal neoplasms.Annals Thoracic Surgery 1984,38:374–9

    Article  CAS  Google Scholar 

  7. Hetzel MR, Nixon C, Edmonstone WM et al. Laser therapy in 100 tracheobronchial tumours.Thorax 1985,40:341–5

    PubMed  CAS  Google Scholar 

  8. Gelb AF, Epstein JD. Neodymium-YttriumAluminium-Garnet laser in lung cancer.Annals of Thoracic Surgery 1987,43:164–7

    Article  PubMed  CAS  Google Scholar 

  9. Stokes LF, Auth DC, Tanaka D et al. Biomedical utility of 1.34μm Nd:YAG laser radiation.IEEE Transactions on Biomedical Engineering 1981,BME-28:297–9

    Google Scholar 

  10. Frank F, Beck OJ, Hessel S, Keiditsch E. Comparative investigations of the effects of the neodymium:YAG laser at 1.06 microns and 1.32 microns on tissue.Lasers Surg Med 1987,6:546–51

    PubMed  CAS  Google Scholar 

  11. Heldwein W, Lehnert P, Wiebecke B et al. Investigation of a new 1.32μm Nd-YAG laser for treatment of bleeding peptic ulcers—experiments on dog stomach.Lasers Med Sci 1987,2:189–94

    Google Scholar 

  12. George PJM, Pearson MC, Edwards D et al. Bronchography in the assessment of patients with lung collapse for laser therapy.Thorax 1990,45:503–8

    PubMed  CAS  Google Scholar 

  13. George PJM, Garrett CPO, Hetzel MR. Role of the neodymium YAG laser in the management of tracheal tumours.Thorax 1987,42:440–4

    Article  PubMed  CAS  Google Scholar 

  14. Beamis JF, Shapshay SM. More about the YAG.Chest 1985,87:277–8

    PubMed  Google Scholar 

  15. Goldhill DR, Hill AJ, Whitburn RH et al. Carboxyhaemoglobin levels, pulse oximetry and arterial blood gases during jet ventilation for Nd-YAG laser bronchoscopy.British Journal of Anaesthesia 1990,65:749–53

    PubMed  CAS  Google Scholar 

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George, P.J.M., Pattison, J.M., Al Jarad, N. et al. Preliminary experience with the 1.32 μm neodymium-YAG laser in the treatment of tracheobronchial malignancy. Laser Med Sci 6, 407–413 (1991). https://doi.org/10.1007/BF02042463

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  • DOI: https://doi.org/10.1007/BF02042463

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