Journal of Plant Growth Regulation

, Volume 3, Issue 1–4, pp 51–63

The comparative cell cycle and metabolic effects of chemical treatments on root tip meristems. III. Chlorsulfuron

  • Thomas L. Rost

DOI: 10.1007/BF02041991

Cite this article as:
Rost, T.L. J Plant Growth Regul (1984) 3: 51. doi:10.1007/BF02041991


Intact and excised cultured pea roots (Pisum sativum L. cv Alaska) were treated with chlorsulfuron at concentrations ranging from 2.8 ×10−4 M to 2.8×10−6 M. At all concentrations this chemical was demonstrated to inhibit the progression of cells from G2 to mitosis (M) and secondarily from G1 to DNA synthesis (S). The S and M phases were not directly affected, but the transition steps into those phases were inhibited. Total protein synthesis was unaffected by treatment of intact roots with 2.8×10−6 M chlorsulfuron. RNA synthesis was inhibited by 43% over a 24-h treatment period. It is hypothesized that chlorsulfuron inhibits cell cycle progression by blocking the G2 and G1 transition points through inhibition of cell cycle specific RNA synthesis.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Copyright information

© Springer-Verlag 1984

Authors and Affiliations

  • Thomas L. Rost
    • 1
  1. 1.Department of BotanyUniversity of CaliforniaDavisUSA

Personalised recommendations