Journal of Plant Growth Regulation

, Volume 3, Issue 1–4, pp 51–63 | Cite as

The comparative cell cycle and metabolic effects of chemical treatments on root tip meristems. III. Chlorsulfuron

  • Thomas L. Rost
Article

Abstract

Intact and excised cultured pea roots (Pisum sativum L. cv Alaska) were treated with chlorsulfuron at concentrations ranging from 2.8 ×10−4 M to 2.8×10−6 M. At all concentrations this chemical was demonstrated to inhibit the progression of cells from G2 to mitosis (M) and secondarily from G1 to DNA synthesis (S). The S and M phases were not directly affected, but the transition steps into those phases were inhibited. Total protein synthesis was unaffected by treatment of intact roots with 2.8×10−6 M chlorsulfuron. RNA synthesis was inhibited by 43% over a 24-h treatment period. It is hypothesized that chlorsulfuron inhibits cell cycle progression by blocking the G2 and G1 transition points through inhibition of cell cycle specific RNA synthesis.

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Copyright information

© Springer-Verlag 1984

Authors and Affiliations

  • Thomas L. Rost
    • 1
  1. 1.Department of BotanyUniversity of CaliforniaDavisUSA

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