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Enzymic synthesis of nucleic acid components carrying label in the nitrogen base and in the ribose part of the molecule

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Abstract

The paper describes an enzymic method for obtaining labelled components of nucleic acids—nucleosides and nucleotides—in reactions catalyzed by a polyenzymic preparation from E. coli B. The method enables highly labelled nucleotides to be obtained through the use of precursors carrying the label at positions unaffected in biosynthesis.

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Authors and Affiliations

  1. Institute of Molecular Genetics, USSR Academy of Sciences, Moscow, (USSR)

    M. D. Frank-Kamenetskaya, G. V. Knizhnikova & N. F. Myasoyedov

Authors
  1. M. D. Frank-Kamenetskaya
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  2. G. V. Knizhnikova
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  3. N. F. Myasoyedov
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Frank-Kamenetskaya, M.D., Knizhnikova, G.V. & Myasoyedov, N.F. Enzymic synthesis of nucleic acid components carrying label in the nitrogen base and in the ribose part of the molecule. Journal of Radioanalytical and Nuclear Chemistry Articles 121, 161–166 (1988). https://doi.org/10.1007/BF02041457

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  • DOI: https://doi.org/10.1007/BF02041457

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