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Preparation of short-lived radioisotope167Tm and its biodistribution in mice

  • Radioanalytical Application
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Abstract

A method for the production of167Tm using the165Ho(α,2n)167Tm nuclear reaction and extraction-chromatography is described. The chemical recovery of Ho is >90%. The final product contains <4 μg/ml of Ho with a radiochemical purity of >99% suitable for medical use. The estimated yield of167Tm is 10–20 μ Ci/μA·h which is comparable with other recent work. Biodistributions of167Tm-citrate in mice indicate that167Tm is an ideal bone and liver tumor scanning agent.

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Authors and Affiliations

  1. Institute of Modern Physics, Academia Sinica, P.O.Box 31, Lanzhou, People's Republic of China

    Niu Fang, Ma Tao-Tao & Teng Ren-Rui

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  1. Niu Fang
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  2. Ma Tao-Tao
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  3. Teng Ren-Rui
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Fang, N., Tao-Tao, M. & Ren-Rui, T. Preparation of short-lived radioisotope167Tm and its biodistribution in mice. Journal of Radioanalytical and Nuclear Chemistry, Articles 124, 353–360 (1988). https://doi.org/10.1007/BF02041327

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  • DOI: https://doi.org/10.1007/BF02041327

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