Abstract
A solvent extraction techniques has been developed to separate iodine from mercury contained in thyroid tissues for the determinations of129I and127I in human thyroid blocks by neutron activation analysis. The tissue samples are digested with a mixture of 5 ml HCl and 1 ml HNO3 in a round-bottomed flask fitted with a condenser running with cold water to avoid any loss of iodine. Iodine is extracted into 0.1 M dihexyl sulfide solution in xylene leaving the majority of the mercury in the aqueous phase. Iodine is adsorbed on activated charcoal packed in quartz tubes either by heating the xylene containing iodine in the presence of oxygen or by heating the aqueous solution obtained after back extracting iodine from xylene using a saturated sulfur dioxide solution. Iodine is desorbed from the charcoal and trapped into a quartz ampule which is sent for neutron activation.
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Singh, N.P., Searing, J.M. & Wreen, M.E. Determination of129I and127I in human thyroid blocks containing mercury as a preservative. Journal of Radioanalytical and Nuclear Chemistry, Articles 124, 301–311 (1988). https://doi.org/10.1007/BF02041323
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DOI: https://doi.org/10.1007/BF02041323