Abstract
In this paper the reactor production of a variety of therapeutic radionuclides of current clinical interest are discussed. Examples include radioisotopes produced by single neutron capture and those which are available from β−/decay of reactor-produced parent radioisotopes. Two examples of generator parents produced by double neutron capture of targets are also discussed. One key example in this category is188W, produced from irradiation of enriched186W. The production of188W in the ORNL High Flux Isotope Reactor and the fabrication and performance of the first production level large-scale clinical prototype188W/188Re generators are also described.
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(Russ) Knapp, F.F., Mirzadeh, S. & Beets, A.L. Reactor production and processing of therapeutic radioisotopes for applications in nuclear medicine. Journal of Radioanalytical and Nuclear Chemistry, Articles 205, 93–100 (1996). https://doi.org/10.1007/BF02040554
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DOI: https://doi.org/10.1007/BF02040554