Abstract
The utilization of carrier-free ionic18F is a convenient method for studying the effects of very low extracellular fluoride concentrations on the metabolism of the cariogenic bacterium Streptococcus mutans. We have developed a method for the preparation of carrier-free aqueous solutions of ionic18F with high specific activity (about 707 Bq/ml). Fluoride distribution and fluoride binding experiments showed that submicromolar fluoride concentrations have already a negative effect on the metabolism of Streptococcus mutans.
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Psapros, N., Duschner, H. Production and use of carrier-free18F in studies on the effect of trace amounts of fluoride on the metabolism of the oral cariogenic bacterium Streptococcus mutans. Journal of Radioanalytical and Nuclear Chemistry, Articles 122, 327–331 (1988). https://doi.org/10.1007/BF02037779
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DOI: https://doi.org/10.1007/BF02037779