Instrumental neutron activation analysis in study of the toxicity of trialkyltin-methacrylic copolymer as an antifouling agent

  • S. M. Lin
  • C. H. Chiang
  • C. L. Tseng
  • M. H. Yang
Physical Methods Section


The analysis of tin in biological materials is rarely reported. In this study, instrumental neutron activation analysis was used to determine the tin together with some other trace elements in various organs of rats treated with trialkyltin-methacrylic copolymer. No appreciable accumulation of tin and variation of distribution of trace elements (Cr, Fe, Zn and Co) in various organs are found. The pathological changes in the liver sections cannot be observed either. This therefore indicates that the toxicity of trialkyltin-methacrylic copolymer is low, if any.


Physical Chemistry Toxicity Inorganic Chemistry Activation Analysis Pathological Change 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    H. W. BARKER, V. RUNTE, Am. J. Epiomiol, 96 (1972) 219.Google Scholar
  2. 2.
    C. H. BENOY, P. A. HOOPER, R. SCHNEIDER, Food Cosmet. Toxicol., 9 (1971) 645.CrossRefPubMedGoogle Scholar
  3. 3.
    Th. ALAJOUANINE, L. DEROBERT, S. THIEFFRY, Rev. Neurol., 98 (1958) 85.PubMedGoogle Scholar
  4. 4.
    J. M. BARNES, H. B. STONER, Pharmacol. Rev., 11 (1959) 211.PubMedGoogle Scholar
  5. 5.
    M. J. MARKS, C. L. WINES, S. P. SHANOR, Toxicol. Appl. Pharmacol., 14 (1969) 627.Google Scholar
  6. 6.
    Z. PELIKAN, E. CERNY, Berufsdermatosen, 16 (1968) 340.PubMedGoogle Scholar
  7. 7.
    W. H. LYLE, Brit. J. Ind. Med., 15 (1958) 193.Google Scholar
  8. 8.
    G. PRVILL, K. ROMPEL, Electroenceph. Clin. Neurophysiol., 29 (1970) 215.Google Scholar
  9. 9.
    L. FRIBERG, G. F. NORDBERG, V. B. VOUK, Handbook on the Toxicology of Metals. Elsevier/North-Holland Biomedical Press, Amsterdam-New York-Oxford, 1979, p. 611.Google Scholar

Copyright information

© Akadémiai Kiadó 1985

Authors and Affiliations

  • S. M. Lin
    • 1
  • C. H. Chiang
    • 1
  • C. L. Tseng
    • 2
  • M. H. Yang
    • 2
  1. 1.Graduate Institute of MedicineKaohsiung Medical CollegeKaohsiungTaiwan(Republic of China)
  2. 2.Institute of Nuclear ScienceNational Tsing Hua UniversityHsinchuTaiwan(Republic of China)

Personalised recommendations