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Optimation of the production of Na18F by use of the Szilard-Chalmers reaction following irradiation of fluorine compounds with 14 MeV neutrons

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Abstract

Studies intended to optimize the production of Na18F, in aqueous solution following irradiation of organic fluorine compounds with 14 MeV neutrons are described. The use of Szilard-Chamers conditions was chosen to enhance the yield of18F, given the low fluxes available and the inherently low cross section of the (n, 2n) reaction. Twenty five potential target compounds were tested. The most suitable one, both in terms of the cost of the target material and of the efficiency of production of water-soluble Na18F, was found to be perfluoro n-hexane. A simple production method for18F− is outlined.

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Authors and Affiliations

  1. Department of Nuclear Engineering, Ben-Gurion University of the Negev, Beersheva, (Israel)

    Z. B. Alfassi & A. P. Kushelevsky

  2. Radiopharmacy Program, School of Pharmacy, University of Southern California, Los Angeles, California, (USA)

    W. Wolf

Authors
  1. Z. B. Alfassi
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  2. A. P. Kushelevsky
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  3. W. Wolf
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Alfassi, Z.B., Kushelevsky, A.P. & Wolf, W. Optimation of the production of Na18F by use of the Szilard-Chalmers reaction following irradiation of fluorine compounds with 14 MeV neutrons. Journal of Radioanalytical and Nuclear Chemistry, Articles 100, 263–268 (1986). https://doi.org/10.1007/BF02037231

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  • DOI: https://doi.org/10.1007/BF02037231

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