14C-labelled propoxur metabolic studies on Anopheles Stephensi from the south coast of Iran

  • M. A. Hossaini
  • A. V. Manouchehri
  • Z. Zareh
Nuclear Methods in Environmental Science
  • 25 Downloads

Abstract

14C-Propoxur (Baygon®) was synthesized through the reaction of o-isopropoxyphenol with methyl isocyanate −14C. The product was isolated chromatographically on Florisil and crystallized from carbon tetrachloride. The purity and structure were confirmed using infrared spectra, melting point, co-chromatography on Florisil column, and silica-gel G thin layer chromatography. The purity was found to be at least 99%. The rate of absorption and other characteristics of14C-propoxur resistance inAnopheles Stephensi from the south coast ot Iran was investigated. The mortality of strain adults was 100% after a one hour exposure when 1 ppm14C-propoxur was used. Moreover, the mortality was not changed when a lower concentration (5 ppm) was used. On the other hand, the absorbance of14C-propoxur in several strains ofA. Stephensi has been determined. The identity and TLC characteristics of products formed after 1 and 2 hours exposure, respectively, to14C-propoxur have also been investigated.

Keywords

Methyl Chromatography Melting Point Thin Layer Thin Layer Chromatography 

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    M. MOTABAR, I. TABIBZADEH, A. V. MANOUCHEHRI, Trop. Georg. Med. 27 (1975) 71.Google Scholar
  2. 2.
    A. V. MANOUCHEHRI, E. JVADIAN, N. ESHGHY, M. MOTABAR, Trop. Georg. Med. 28 (1976) 228.Google Scholar
  3. 3.
    J. KIRSHNA, G. H. WYMAN DOROUGH, J. E. CASIDA, J. Agri. Food Chem., 10 (1960) 462.CrossRefGoogle Scholar
  4. 4.
    R. L. METCALF, F. OSMAN, T. R. FULKUTO, J. Econ. Entomol., 60 (1967) 445.PubMedGoogle Scholar
  5. 5.
    S. P. SHRIVASTAVA, M. TSUKAMOTO, J. F. CASIDA, J. Econ. Entomol., 62 (1969) 483.Google Scholar

Copyright information

© Akadémiai Kiadó 1984

Authors and Affiliations

  • M. A. Hossaini
    • 1
  • A. V. Manouchehri
    • 1
  • Z. Zareh
    • 1
  1. 1.Nuclear Research CenterAtomic Energy Organization of IranTehran(Iran)

Personalised recommendations