14C-labelled propoxur metabolic studies on Anopheles Stephensi from the south coast of Iran

  • M. A. Hossaini
  • A. V. Manouchehri
  • Z. Zareh
Nuclear Methods in Environmental Science


14C-Propoxur (Baygon®) was synthesized through the reaction of o-isopropoxyphenol with methyl isocyanate −14C. The product was isolated chromatographically on Florisil and crystallized from carbon tetrachloride. The purity and structure were confirmed using infrared spectra, melting point, co-chromatography on Florisil column, and silica-gel G thin layer chromatography. The purity was found to be at least 99%. The rate of absorption and other characteristics of14C-propoxur resistance inAnopheles Stephensi from the south coast ot Iran was investigated. The mortality of strain adults was 100% after a one hour exposure when 1 ppm14C-propoxur was used. Moreover, the mortality was not changed when a lower concentration (5 ppm) was used. On the other hand, the absorbance of14C-propoxur in several strains ofA. Stephensi has been determined. The identity and TLC characteristics of products formed after 1 and 2 hours exposure, respectively, to14C-propoxur have also been investigated.


Methyl Chromatography Melting Point Thin Layer Thin Layer Chromatography 
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Copyright information

© Akadémiai Kiadó 1984

Authors and Affiliations

  • M. A. Hossaini
    • 1
  • A. V. Manouchehri
    • 1
  • Z. Zareh
    • 1
  1. 1.Nuclear Research CenterAtomic Energy Organization of IranTehran(Iran)

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