Skip to main content
SpringerLink
Log in

Preparation of high specific activity radiotracers for radioanalytical studies

  • Radiochemical and Radioanalytical Techniques
  • Published:
Journal of Radioanalytical and Nuclear Chemistry Aims and scope Submit manuscript

Abstract

High specific activity radiotracers are very suitable for studies related to the toxicological impact of trace elements onto human health. In order to investigate the metabolic behaviour of Low Level Exposure (LLE) to trace elements, it is necessary to carry out in-vitro and in-vivo experiments with tracers whose concentration is of the same order of magnitude as the present environmental exposure values (ng-μg/kg day). Preparations, separations and purifications of some No Carrier Added (NCA) radiotracers (48V,95m,96Tc,195m,g,197m,gHg,199Au,202Tl) produced by either cyclotron or nuclear reactor irradiation, are presented and discussed. This work reviews the more recent advances in this field carried out by our groups.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. A. P. WOLF, J. Nucl. Med., 22 (1981) 392.

    Google Scholar 

  2. R. PIETRA, E. SABBIONI, M. GALLORINI, E. ORVINI, J. Radioanal. Nucl. Chem., 102 (1986) 69.

    Article  Google Scholar 

  3. E. SABBIONI, L. GOETZ, C. BIRATTARI, M. BONARDI, Sci. Total Env., 17 (1981) 257.

    Article  Google Scholar 

  4. M. LEDERER, V. SHYRLEY, Table of Isotopes, Wiley, NY, 1978.

    Google Scholar 

  5. E. BROWNE, R. B. FIRESTONE, Table of Radioactive Isotopes, Wiley, NY, 1986.

    Google Scholar 

  6. M. BONARDI, The contribution to nuclear data for medical radioisotope production from the Milan Cyclotron Laboratory, Report INDC(NBS)-195/GZ, IAEA, Vienna, 1988, p. 98.

    Google Scholar 

  7. H. A. WAPSTRA, K. BOS, ADNDT, 19 (1977) 177.

    Article  Google Scholar 

  8. M. BONARDI, M. SILARI, Phys. Med., 1 (1988) 23, 2 (1988) 831.

    Google Scholar 

  9. R. BASSINI, C. BIRATTARI, M. BONARDI, et al., An absolute method for the energy calibration of cyclotron geams. Proc. 12th Int. Conf. on Cyclotrons and their Application, Berlin, World Scientific Publ. Co., Singapore, 1989, p. 291.

    Google Scholar 

  10. E. SABBIONI, E. MARAFANTE, L. GOETZ, C. BIRATTARI, Radiochem. Radioanal. Letters, 31 (1977) 39.

    Google Scholar 

  11. U. SCHINDEWOLF, J. W. IRVINE, Anal. Chem., 30 (1958) 906.

    Article  Google Scholar 

  12. F. W. STRELOW, C. H. WEINERT, C. ELOFF, Anal. Chem., 44 (1972) 2352.

    Article  Google Scholar 

  13. R. IWATA, K. IWAI, T. IDO, KIMURA, J. Radioanal. Nucl. Chem., 134 (1989) 303.

    Google Scholar 

  14. E. SABBIONI, M. BONARDI, G. TANET, LI DA-KANG, M. GALLORINI et al., 134 (1989) 199.

  15. F. W. E. STRELOW, R. RETHEMEYER, C. J. C. BOTHMA, Anal. Chem., 37 (1965) 106.

    Article  Google Scholar 

  16. E. SABBIONI, J. EDEL, L. GOETZ et al., Biol. Trace Element Res., 12 (1987) 199.

    Google Scholar 

  17. J. KORKISH, Handbook of Ion Exchange Resins: Their Application to Inorganic Analytical Chemistry, Vol. IV, CRC Press, Boca Raton, FL, 1989, p. 248.

    Google Scholar 

  18. L. GOETZ, E. SABBIONI, E. MARAFANTE, J. EDEL-RADE, C. BIRATTARI, M. BONARDI, J. Radioanal. Chem., 67 (1981) 183.

    Google Scholar 

  19. M. BONARDI, C. BIRATTARI, A. SALOMONE, J. Label. Comp. Radiopharm., 19 (1982) 1330.

    Google Scholar 

  20. Unpublished results.

  21. C. BIRATTARI, M. BONARDI, E. SABBIONI et al., Gamma-emitting technetium radiotracer production for waste disposal studies at Milan AVF Cyclotron. Report INFN/TC-84/24, Frascati, Roma, 1984.

  22. C. BIRATTARI, M. BONARDI, Excitation functions for195m,gHg/195mAu generator production. Proc. 3rd World Congress on Nuclear Medicine and Biology, Paris, France, 1982. Pergamon Press, Paris, 1982, p. 1119.

    Google Scholar 

  23. M. BONARDI, F. GROPPI, C. BIRATTARI, G. ALBERTI, J Label. Comp. Radiopharm., 26 (1989) 185.

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Centre for Radiochemistry and Activation Analysis, CNR, Via Taramelli 12, 27100, Pavia, (Italy)

    M. Gallorini

  2. Accelerators and Applied Superconductivity Laboratory, LASA, University and INFN, Milano, (Italy)

    C. Birattari & M. Bonardi

  3. University of Ferrara, Ferrara, (Italy)

    L. Magon

  4. Institute of the Environment, JRC-Ispra, Varese, (Italy)

    E. Sabbioni

Authors
  1. M. Gallorini
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. C. Birattari
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. M. Bonardi
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. L. Magon
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. E. Sabbioni
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Gallorini, M., Birattari, C., Bonardi, M. et al. Preparation of high specific activity radiotracers for radioanalytical studies. Journal of Radioanalytical and Nuclear Chemistry, Articles 160, 549–561 (1992). https://doi.org/10.1007/BF02037130

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02037130

Keywords

Search

Navigation