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Synthesis and radiolabelling of N-acetanilidoiminodiacetic acid analogues with MEK extracted99mTc

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Abstract

Labelling of N-(2,6-diethylacetanilido), N-(p-n-butylacetanilido,N-(p-methoxyacetanilido) and N-acetanilido-iminodiacetic acid analogues with99mTc obtained by MEK extraction has been studied. The acetanilido IDA analogues were synthesized using the condensation reaction between nitrilotriacetic acid anhydride and the corresponding anilines. Conditions are described to label these four HIDA analogues using MEK extracted99mTc with high and reproducible radiochemical purity.

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Authors and Affiliations

  1. Radiopharmaceuticals Division, bhabha Atomic Research Centre, Trombay, 400 085, Bombay, (India)

    D. V. S. Narasimhan & R. S. Mani

Authors
  1. D. V. S. Narasimhan
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  2. R. S. Mani
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Narasimhan, D.V.S., Mani, R.S. Synthesis and radiolabelling of N-acetanilidoiminodiacetic acid analogues with MEK extracted99mTc. Journal of Radioanalytical and Nuclear Chemistry, Articles 88, 301–312 (1985). https://doi.org/10.1007/BF02037006

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  • DOI: https://doi.org/10.1007/BF02037006

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