Skip to main content
Log in

Determination of the natural level of human intra-thyroid iodine by instrumental neutron activation analysis

  • Published:
Journal of Radioanalytical and Nuclear Chemistry Aims and scope Submit manuscript

Abstract

The iodine thyroid content of 57 relatively healthy men and women 14–60 years old was studied using instrumental neutron activation analysis. Two methods were used: analysis of whole glands and the analysis of lyophilized samples weighing 50 mg each. Very good agreement between results was obtained. It was shown that the total iodine content, concentration and weight did not depend on age and sex. The typical mean thyroid parameters were found for healthy people of non-endemically goitrous regions where iodated food is not eaten. Average thyroid weight was 14.2g, iodine concentration was 350 μg/g of wet weight and thus total iodine content was 5 mg.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Subscribe and save

Springer+ Basic
EUR 32.99 /Month
  • Get 10 units per month
  • Download Article/Chapter or Ebook
  • 1 Unit = 1 Article or 1 Chapter
  • Cancel anytime
Subscribe now

Buy Now

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. WERNER's The Thyroid. A Fundamental and Clinical Text, J. B. Lippincott Company, Philadelphia, 1986.

  2. F. COTTINO, G. FREGOLA, G. ZOPPETTI, Annales Endocrinologie, 20 (1959) 445.

    Google Scholar 

  3. D. A. FISHER, T. H. ODDIE, J. Clin. Endocr., 29 (1969) 721.

    PubMed  Google Scholar 

  4. G. B. BELLING, in: Trace Analysis of Biological Materials: Principles and Methods for Determination of Trace Elements, Elsevier, Amsterdam, 1988, p. 519.

    Google Scholar 

  5. A. M. ERMANS, J. E. DUMONT, P. A. BASTENIE, J. Clin. Endocr., 23 (1963) 539.

    Google Scholar 

  6. V. Ye. ZAICHICK, Yu. S. RYABUKHIN, A. V. TKACHEV, Med. Radiologiya, 4 (1968) 59 (in Russian).

    Google Scholar 

  7. Report of the Task Group on Reference Man, ICRP No. 23, Pergamon Press, Oxford, 1975.

  8. H. KOLMITZ, R. E. REMINGTON, Endocrinology, 17 (1933) 563.

    Google Scholar 

  9. H. AGERBAEK, Acta Med. Scand., 196 (1974) 505.

    PubMed  Google Scholar 

  10. P. HELLSTERN, H. E. KELLER, B. WEINHEIMER, H. WESCH, Clin. Endocrinology, 9 (1978) 351.

    Google Scholar 

  11. D. G. ROKHLIN, V. P. ZADVORNOVA, Ionizing Irradiation for Thyroid Cancer Diagnostics and Treatment, Meditsina, Leningrad, 1972.

    Google Scholar 

  12. K. IMAMURA, J. SASAKI, T. LJI, K. SOMEYA, M. FUJII, Radioisotopes, 26 (1977) 858.

    PubMed  Google Scholar 

  13. J. PICKWORTH, J. Mental Sciences, (1925) 703.

  14. GUTMAN, E. M. BENEDICT, B. BAXTER, W. W. PALMER, J. Biol. Chem., 98 (1932) 303.

    Google Scholar 

  15. V. S. MAYAT, I. M. SEGAL, A. M. FELDT, Sovetskaya Klinika, 17 (1932) 330 (in Russian).

    Google Scholar 

  16. W. ELMER, Fiziologia i Pathologia Przennany Jodu, Krakow, 1936.

  17. H. LOHR, H. WILMANNS, H. SCHROEDER, Z. Gesamte Experimentelle Medizin, 109 (1941) 730.

    Google Scholar 

  18. E. KLEIN, D. REINWEIN, Acta Endocr. (Kbh), 41 (1962) 170.

    Google Scholar 

  19. K. E. AROSEIUS, Scand. J. Clin. Endocr., 16 (1964) 440.

    Google Scholar 

  20. P. A. HEEDMAN, B. JACOBSON, J. Clin. Endocr., 24 (1964) 246.

    PubMed  Google Scholar 

  21. L. J. DeGROOT, J. Clin. Endocr., 26 (1965) 149.

    Google Scholar 

  22. A. COSTA, R. BACCI, M. CARLI, F. COTTINO, G. LISTTORTO, G. MAGRO, G. ZOPPETTI, Folia Endocrinologica, 20 (1967) 284.

    PubMed  Google Scholar 

  23. W. H. BEIERWALTES, H. N. WAGNER, R. L. VOUGHT, A. T. MASI, in: Principles of Nuclear Medicine, W. B. Saunders, Philadelphia, 1968, p. 302.

    Google Scholar 

  24. R. A. McMAHON, M. L. M. PARKER, M. C. McKINNON, Med. J. Australia, 20 (1968) 210.

    Google Scholar 

  25. J. BRUNE, P. O. WESTER, Anal. Chim. Acta, 52 (1972) 81.

    Article  Google Scholar 

  26. N. JAMAGATA, T. JAMAGATA, J. Rad. Res., 13 (1972) 81.

    Google Scholar 

  27. W. T. BINNERTS, H. A. DAS, Methods Biochem. Anal., 22 (1974) 251.

    PubMed  Google Scholar 

  28. L. KOSTA, V. ZELENKO, V. RAVNIK, M. LEVSTEK, M. DERMELI, A. R. BYRNE, in: Comparative Studies of Food and Environment Contamination, IAEA, Vienna, 1974, p. 541.

    Google Scholar 

  29. V. Ye. ZAICHICK, N. I. KONSTANTINOVA, N. P. ROSLYAKOV, L. K. NIKITENKO, in: Neutron Application in Medicine, Obninsk, 1976, p. 69 (in Russian).

  30. L. L. OLIVER, R. V. BALLAD, O. K. MANUEL, Health Phys., 42 (1982) 425.

    PubMed  Google Scholar 

  31. J. HANDL, A. PFAU, F. W. HUTH, Health Phys., 58 (1990) 609.

    PubMed  Google Scholar 

  32. E. D. WILLIAMS, I. DONIACH, O. BJARNASON, W. MICHIE, Cancer, 39 (1977) 215.

    PubMed  Google Scholar 

  33. S. THORESEN, E. GLATTRE, A. A. JOHANSEN, Tidsskr. Nor. Lageforen, 31 (1986) 2616.

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Zaichick, V.Y., Choporov, Y.Y. Determination of the natural level of human intra-thyroid iodine by instrumental neutron activation analysis. Journal of Radioanalytical and Nuclear Chemistry, Articles 207, 153–161 (1996). https://doi.org/10.1007/BF02036535

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02036535

Keywords

Navigation