Journal of Radioanalytical and Nuclear Chemistry

, Volume 195, Issue 1, pp 123–132 | Cite as

Neutron activation analysis of saliva: Application in clinical chemistry, environmental and occupational toxicology

  • V. Zaichick
  • A. Tsyb
  • S. Bagirov
Application of Radioanalytical Techniques to Biological and Biomedical Sciences


The contents of 21 chemical elements (Ag, Br, Ca, Cl, Co, Cr, Cs, Fe, Hg, K, Mg, Mn, N, Na, P, Rb, Sb, Sc, Se, Sr, Zn) in mixed non-stimulated saliva of 52 relatively healthy people were assessed by activation using 14 MeV neutrons and nuclear reactor neutrons. The study included 45 women and 7 men, aged 18 to 35. The dependence of salivary composition upon sex, age, time-of-day and time-of-year was studied. The saliva of 22 men, involved in the clean up operation after the Chernobyl accident, was also studied. There existed clear circadian variations in the amount of Na, Sc and Cr contained in the saliva and a tendency to circadian variations for the amount of Cl, Co, Br and Rb. Neither sex, age, nor time-of-year influenced the contents of 21 chemical elements examined. The only exception to this finding was with Hg, whose content increases with age. The analysis of the cleaners' saliva made it possible to find considerable metabolic changes of Ca and some other chemical elements.


Physical Chemistry Inorganic Chemistry Activation Analysis Chemical Element Neutron Activation 
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Copyright information

© Akadémiai Kiadó 1995

Authors and Affiliations

  • V. Zaichick
    • 1
  • A. Tsyb
    • 1
  • S. Bagirov
    • 1
  1. 1.Medical Radiological Research CentreObninskRussia

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