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Determination of trace element impurities in aspirin tablets by neutron activation analysis


Twenty five trace and minor elements (aluminium, arsenic, barium, bromine, cerium, chlorine, cobalt, chromium, cesium, europium, iron, hafnium, potassium, magnesium, manganese, sodium, rubidium, antimony, scandium, selenium, strontium, thorium, titanium, vanadium and zinc) in five different Egyptian aspirin brands (Aspo, Askin, Aspocid, Aspeol and Rivo) have been determined by instrumental neutron activation analysis. It has been concluded that the concentration of arsenic, barium, bromine, cobalt, chromium, iron (except in Aspocid), magnesium, manganese, rubidium, selenium, strontium and zinc in the Egyptian brands is below or within the concentration range reported for these elements in 16 American aspirin and aspirin-like brands.

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Iskander, F.Y., Klein, D.E. & Bauer, T.L. Determination of trace element impurities in aspirin tablets by neutron activation analysis. Journal of Radioanalytical and Nuclear Chemistry, Articles 97, 353–357 (1986).

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  • Cobalt
  • Arsenic
  • Aspirin
  • Selenium
  • Vanadium