Journal of Radioanalytical and Nuclear Chemistry

, Volume 97, Issue 2, pp 353–357 | Cite as

Determination of trace element impurities in aspirin tablets by neutron activation analysis

  • F. Y. Iskander
  • D. E. Klein
  • T. L. Bauer
Physical Methods Section


Twenty five trace and minor elements (aluminium, arsenic, barium, bromine, cerium, chlorine, cobalt, chromium, cesium, europium, iron, hafnium, potassium, magnesium, manganese, sodium, rubidium, antimony, scandium, selenium, strontium, thorium, titanium, vanadium and zinc) in five different Egyptian aspirin brands (Aspo, Askin, Aspocid, Aspeol and Rivo) have been determined by instrumental neutron activation analysis. It has been concluded that the concentration of arsenic, barium, bromine, cobalt, chromium, iron (except in Aspocid), magnesium, manganese, rubidium, selenium, strontium and zinc in the Egyptian brands is below or within the concentration range reported for these elements in 16 American aspirin and aspirin-like brands.


Cobalt Arsenic Aspirin Selenium Vanadium 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    L. BONIFORTI, M. G. QUAGLIA, N. VIOLANTE, Eur. J. Mass. Spectrom. Biochem., Med. Environ. Res., 1 (1980) 179.Google Scholar
  2. 2.
    F. NAMIGOHAR, J. KHORRAMI, Ann. Pharm. Fr., 34 (1976) 457.PubMedGoogle Scholar
  3. 3.
    K. W. STREET, Jr., G. H. SCHENK, J. Pharm. Sci., 70 (1981) 641.PubMedGoogle Scholar
  4. 4.
    S. K. BAKER, S. NIAZI, J. Pharm. Sci., 72 (1983) 1020.PubMedGoogle Scholar
  5. 5.
    K. WELCAWSKA, M. KLOSIN, Farm. Pol., 32 (1976) 827.Google Scholar
  6. 6.
    Y. K. AGRAWAL, Sci. Cult., 46 (1980) 309.Google Scholar
  7. 7.
    J. A. VINSON, D. M. KOZAK, Am. J. Pharm. Educ., 42 (1978) 291.Google Scholar
  8. 8.
    F. Y. ISKANDER, J. Radioanal. Nucl. Chem., 89 (1985) 511.Google Scholar
  9. 9.
    F. Y. ISKANDER, J. Radioanal. Nucl. Chem., 91 (1985) 191.Google Scholar
  10. 10.
    B. P. HICHWA, D. D. PUN, D. WANG, IEEE Trans. Nucl. Sci. NS, 28 (1981) 1410.Google Scholar

Copyright information

© Akadémiai Kiadó 1986

Authors and Affiliations

  • F. Y. Iskander
    • 1
  • D. E. Klein
    • 1
  • T. L. Bauer
    • 1
  1. 1.Nuclear Engineering Teaching Laboratory, Department of Mechanical EngineeringThe University of Texas at AustinAustin(USA)

Personalised recommendations