Advertisement

The determination of boron in biological materials by neutron irradiation and prompt gamma-ray spectrometry

  • N. I. Ward
Article

Abstract

A prompt-gamma neutron activation technique has been developed using the (n, γ) apparatus situated at the O degree through-tube of the Imperial College CONSORT II Reactor with a thermal neutron flux at the target position of approximately 2×106 n cm−2 sec−1, and a Compton-suppression system involving a lithium-drifted germanium (Ge(Li)) detector and a sodium iodide anti-Compton shield. Boron levels of 1–5 μg g−1 (detection limit 0.05 μg B for 10,000 sec period of measurement) can be attained using the Compton-suppression system with graphical inter-polation correction for the 472 keV sodium-ray peak contribution to the Doppler-broadened 478 keV boron gamma-ray peak resulting from the10B(n, α)7Li reaction. Very good agreement is reached for boron levels compared using this system for various Standard Reference Materials and other published values. Measurement of the boron content of bone and tooth samples from rheumatoid arthritis individuals shows lower levels, (p<0.05); 16.13±7.53 μg g−1, when compared with a control population; 19.79±4.18 μg g−1. A positive correlation existed between the boron content of bone and tooth material for each study group. Results indicate that boron availability may be associated with rheumatoid arthritis.

Keywords

Boron Boron Content Thermal Neutron Flux Sodium Iodide Tooth Sample 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    K. WASHINGTON, Ann. Bot. (London), 37 (1923) 629.Google Scholar
  2. 2.
    G. V. IYENGAR, W. E. KOLLMER, H. J. M. BOWEN, The Elemental Composition of Human Tissues and Body Fluids, Verlag Chemie, Weinheim, New York, 1978.Google Scholar
  3. 3.
    N. N. GREENWOOD, Boron: Chapter II: Comprehensive Inorganic Chemistry-Volume 1, Pergamon Press, Oxford, 1973, p. 693.Google Scholar
  4. 4.
    E. J. UNDERWOOD, Trace Elements in Human and Animal Nutrition, Academic Press, New York, 1977, p. 436.Google Scholar
  5. 5.
    P. J. TEMPLE, S. N. LINZON, J. Air Pollut. Control Assoc., 26 (1976) 499.Google Scholar
  6. 6.
    E. S. GLADNEY, L. E. WANGEN, D. B. CURTIS, E. T. JURNEY, Environ. Sci. Tech., 12 (1978) 1084.Google Scholar
  7. 7.
    F. T. BINGHAM, Trace Elements in the Environments, American Chemical Society, Washington, D. C., 1973 p. 130.Google Scholar
  8. 8.
    D. PURFES, E. J. MACKENZIE, Plant Soil, 40 (1974) 231.Google Scholar
  9. 9.
    D. G. NEARY, G. SCHNEIDER, D. P. WHITE, Soil Sci. Soc. Am. Proc., 39 (1975) 981.Google Scholar
  10. 10.
    H. K. L. GUPTA, D. F. BOLTZ, Anal. Lett., 4 (1971) 161.Google Scholar
  11. 11.
    P. LANZA, P. L. BULDINI, Anal. Chim. Acta, 70 (1974) 341.Google Scholar
  12. 12.
    E. E. PICKETT, J. C. M. PAU, S. R. KOIRTYOHANA, J. Assoc. Offic. Anal. Chem., 54 (1971) 796.Google Scholar
  13. 13.
    W. J. MAECK, Anal. Chem., 35 (1963) 62.Google Scholar
  14. 14.
    W. W. HARRISON, N. J. PRAKASH, Anal. Chim. Acta, 49 (1970) 151.Google Scholar
  15. 15.
    Y. HAYASHI, S. MATSUSHITA, T. KUMAMARU, Y. YAMAMOTO, Talanta, 20 (1973) 414.Google Scholar
  16. 16.
    M. M. ASHRY, Geochim. Cosmochim. Acta, 37 (1973) 2449.Google Scholar
  17. 17.
    R. M. CARLSON, J. L. PAUL, Anal. Chem., 40 (1968) 1292.Google Scholar
  18. 18.
    B. S. CARPENTER, R. L. MYKLEBUST, Anal. Chim. Acta, 81 (1976) 409.Google Scholar
  19. 19.
    F. THEVENOT, J. CUEILLERON, Analusis, 5 (1977) 105.Google Scholar
  20. 20.
    T. L. ISENHOUR, G. H. MORRISON, Anal. Chem., 38 (1966) 167.Google Scholar
  21. 21.
    R. HENKELMAN, E. T. BORN, J. Radioanal. Chem., 16 (1973) 473.Google Scholar
  22. 22.
    E. S. GLADNEY, E. T. JURNEY, D. B. CURTIS, Anal. Chem., 48 (1976) 2139.PubMedGoogle Scholar
  23. 23.
    S. A. KERR, W. V. PRESTWICH, T. J. KENNETT, D. M. SHAW, J. Radioanal. Chem., 57 (1980) 525.Google Scholar
  24. 24.
    G. D. BURHOLT, T. D. MACMAHON, J. Radioanal. Chem., 53 (1979) 365.Google Scholar
  25. 25.
    M. THEEN, A Study of the Prompt and Delayed Gamma-rays following Thermal Neutron Capture in107Ag and109Ag, PhD thesis, Imperial College, May, 1977, p. 125.Google Scholar
  26. 26.
    D. A. BECKER, Environmental Sample Banking-Research and Methodology, Trace Substances in Environmental Health-X, D. D. HEMPHILL (Ed.), University of Missouri, 1976.Google Scholar
  27. 27.
    B. S. CARPENTER, National Bureau of Standards, Washington D. C., Report, 1976.Google Scholar
  28. 28.
    International Atomic Energy Agency, Lab/243, Information Sheet Certified Reference Material, Soil-5, October, 1978.Google Scholar
  29. 29.
    H. J. M. BOWEN, private communication, 1980.Google Scholar
  30. 30.
    S. A. KERR, N. M. SPYROU, J. Radioanal. Chem., 44 (1978) 159.Google Scholar
  31. 31.
    W. NEUWIRTH, W. PIETSCH, K. RICHTER, U. HAUSER, Z. Physik., A275 (1975) 209.Google Scholar
  32. 32.
    R. E. NEWNHAM, Boron is Essential-It Corrects and Prevents Arthritis, presented at Conference of the New Zealand Trace Element Group, Massey University, Palmerston North, New Zealand, Aug. 7–8, 1984.Google Scholar
  33. 33.
    A. J. PARR, B. C. LOUGHMAN, Boron and Membrane Function in Plants. Metals and Micro Elements in Plants, Chapter 6, Robb and Pierpoint, Academic Press, 1983.Google Scholar

Copyright information

© Akadémiai Kiadó 1987

Authors and Affiliations

  • N. I. Ward
    • 1
  1. 1.Reactor CentreImperial College at Silwood ParkAscot(England)

Personalised recommendations