Abstract
Epithermal neutron activation analysis (ENAA) was applied to measure quantitatively Cd and other elements in bone samples from control and Cd-fed rats. This method was found to be non-destructive to the bone samples, with no sign of “radiolytic charring” and was sensitive enough to detect and quantify Cd in bone samples at normal levels for mammals (viz. 0.5–1.0 μg/g) and higher. Two different thermal neutron shield materials were utilized, namely cadmium and boron. The boron shield resulted in a 27% improvement in the detection limit of Cd in bone. The accuracy of ENAA for Cd was assessed by intercomparison with electrothermal atomic absorption spectrophotometry (ETAAS), and the results were in fair agreement (±23%) with those from ENAA.
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P. F. SCHMIDT, R. BARCKHAUS, W. KLEIMEIER, Trace Elem. Med., 3 (1986) 19.
H. A. SCHROEDER, J. Chronic Disease, 18 (1978) 647.
T. KJELLSTROM, Effects on Bone, Vitamin D, and Calcium Metabolism, in: L. FRIBERG, C. G. ELINDER, T. KJELLSTROM, G. F. NORDBERG (Eds), Cadmium and Health: A Toxicological and Epidemiological Appraisal-II, CRC Press, Boca Raton, Fla., 1986.
N. YAMAGATA, Analytical Methods, in: K. TSUCHIYA (Ed.), Cadmium Studies in Japan: A Review-II, Elsevier, Tokyo, 1978.
J. D. BLAINEY, R. G. ADAMS, D. B. BREWER, T. C. HARVEY, Br. J. Ind. Med., 37 (1980) 278.
F. W. BONNER, L. J. KING, D. V. PARKE, Chem. Biol. Interact., 29 (1980) 369.
H. IGUCHI, H. SANO, Japan. J. Hyg., 35 (1980) 224.
K. KAWAI, K. FUKUDA, M. KIMURA, Effects and Dose-Response Relationships of Toxic Metals, G. F. NORDBERG (Ed.), Elsevier, Amsterdam, 1976, p. 343.
L. A. CURRIE, Anal. Chem., 40 (1968) 586.
S. KRISHNAN, personal communication, Toronto General Hospital, March 1986.
R. VAN DER LINDEN, F. DE CORTE, P. VAN DEN WINKEL, J. HOSTE, J. Radioanal. Chem., 11 (1972) 133.
D. BRUNE, K. JIRLOW, Nukleonik, 6 (1964) 242.
O. T. HOGDAHL, Radiochemical Methods of Analysis, IAEA, Geneva, 1965.
D. DE SOETE, R. GIJBELS, J. HOSTE, Neutron Activation Analysis, in: P. J. ELVING, I. M. KOLTHOFF (Eds), A Series of Monographs on Analytical Chemistry and its Applications, John Wiley and Sons, London, 1972, p. 34.
S. M. W. LUI, M. A. Sc. Thesis, University of Toronto, 1988.
A. O. BRUNFELT, E. STEINNES, Anal. Chim. Acta, 48 (1969) 13.
N. V. BAGDAVADZE, L. M. MOSULISHVILI, J. Radioanal. Chem., 24 (1975) 65.
H. G. MEYER, J. Radioanal. Chem., 7 (1971) 67.
P. NICAUD, A. LAFITTE, A. GROS, Arch. Mal. Prof. Med. Trav. Secur. Soc., 4 (1942) 192.
D. C. STUART, D. E. RYAN, Can. J. Chem., 59 (1981) 1470.
K. N. DE SILVA, P. D. THESIS, Dalhousie University, 1981.
F. ROSSITTO, M. TERRANI, S. TERRANI, Nucl. Instrum. Methods, 103 (1972) 77.
L. E. WANGEN, E. S. GLADNEY, Anal. Chim. Acta, 96 (1978) 271.
IAEA, Intercomparison of Minor and Trace Elements in IAEA Animal Bone (H-5), Progress Report No. 1, 1982.
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Dowlati, R., Jervis, R.E. Determination of trace cadmium and other elements in bone by epithermal neutron activation analysis. Journal of Radioanalytical and Nuclear Chemistry, Articles 150, 455–463 (1991). https://doi.org/10.1007/BF02035332
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DOI: https://doi.org/10.1007/BF02035332