Skip to main content

Utility of ceruletide in promoting intestinal opacification for abdominal and pelvic computed tomography

Abstract

An analysis of the utility of parenteral ceruletide, a cholecystokinin-like synthetic decapeptide, in promoting bowel opacification for computed tomography (CT) scanning was performed. Abdominal and pelvic CT scans of 85 patients who had received intramuscular ceruletide following oral contrast administration and of 85 control patients were reviewed and the degree of bowel opacification evaluated. No significant advantage was conferred by ceruletide in opacifying the stomach or major part of the small intestine. However, a statistically significant difference was found between the 2 groups in the presence or absence of contrast in the terminal ileum and right colon. Contrast was detected in the terminal ileum in 52 experimental compared with 35 control patients (p<0.009) and in the right colon in 56 experimental and 39 control subjects (p<0.01). Intramuscular administration of ceruletide will be helpful when terminal ileal opacification is essential or in patients in whom colonic opacification is desired but rectal contrast contraindicated.

This is a preview of subscription content, access via your institution.

References

  1. Marks WM, Goldberg HI, Moss AA, Koehler RF, Federle MP: Intestinal pseudotumors: a problem in abdominal computed tomography solved by directed techniques.Gastrointest Radiol 5:155–160, 1980

    PubMed  Google Scholar 

  2. Struck KJ, Kuhns LR: Improved visualization of the pancreatic tail after maximum distension of the stomach.J Comput Assist Tomogr 5:509–512, 1979

    Google Scholar 

  3. Kaye MD, Young SW, Hayward R, Castellino RA: Gastric pseudotumor on CT scanning.AJR 135:190–193, 1980

    PubMed  Google Scholar 

  4. Goldberg HI: Computed tomographic evaluation of the gastrointestinal tract in diseases other than primary adenocarcinoma. In Goldberg HI (ed):Interventional Radiology and Diagnostic Imaging Modalities. San Francisco: University of California Press, 1982, pp 237–250

    Google Scholar 

  5. Robbins AH, Wetzner SM, Landy MD: Ceruletide assisted examination of the small bowel.AJR 134:343–347, 1980

    PubMed  Google Scholar 

  6. Sargent EN, Halls JM, Colletti P, Wieles M: Efficacy and tolerance of ceruletide in radiology of the small intestine.Radiology 136:57, 1982

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and Permissions

About this article

Cite this article

Demas, B.E., McCarthy, S.M., Moss, A.A. et al. Utility of ceruletide in promoting intestinal opacification for abdominal and pelvic computed tomography. Gastrointest Radiol 11, 197–199 (1986). https://doi.org/10.1007/BF02035069

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02035069

Key words

  • Ceruletide
  • Bowel opacification
  • Computed tomography, abdomen