Summary
I.v. administration of lysine acetylsalicylate inces autophagy in mouse liver cells. Single and multiple membrane-bounded vacuoles were found. The latter seems to be an unusual morphological form of the sequestration process. These findings could express a transitory sublethal liver cell injury induced by the drug.
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Acknowledgments. The authors are indebted to Mrs M. T. Correia and to Mrs M. E. Pereira for technical assistance.
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aguas, A.P., Soares, J.O. & Moura Nunes, J.F. Autophagy in mouse hepatocytes induced by lysine acetylsalicylate. Experientia 34, 1618–1619 (1978). https://doi.org/10.1007/BF02034711
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DOI: https://doi.org/10.1007/BF02034711