Experientia

, Volume 34, Issue 12, pp 1600–1601 | Cite as

The influence of hyperosmolality on heart function

  • G. Pogátsa
  • E. Dubecz
Physiologica

Summary

Hyperosmolality produces a reduction in myocardial water content, an increase in ventricular stiffness and coronary blood flow, and a decrease in ventricular performance. The alterations of myocardial dehydration and ventricular stiffness are more pronounced in glucose-induced, and those of ventricular performance in urea-induced hyperosmolality.

Keywords

Blood Flow Dehydration Coronary Blood Flow Heart Function Ventricular Performance 

References

  1. 1.
    A. Aviram, A. Pfau, J.W. Czaczkes and T.D. Ullmann, Am. J. Med.42, 648 (1967).PubMedGoogle Scholar
  2. 2.
    M. Fulop, A. Rosenblatt, S.M. Kreitzer and B. Gerstenhaber, Diabetes24, 594 (1975).PubMedGoogle Scholar
  3. 3.
    S.T. Giammona, P.R. Luris and W.E. Segar, Circulation28, 1096 (1963).PubMedGoogle Scholar
  4. 4.
    A. Hyvärinen and E.A. Nikkilä, Clin. chim. Acta7, 140 (1962).PubMedGoogle Scholar
  5. 5.
    J.J. Coulomba and L. Favreau, Clin. Chem.9, 102 (1963).PubMedGoogle Scholar
  6. 6.
    S. Juhász-Nagy, E. Dubecz, G. Pogátsa and Gy. Gábor, Experientia31, 945 (1975).PubMedGoogle Scholar
  7. 7.
    G. Diamond and J.S. Forrester, Circulation45, 11 (1972).PubMedGoogle Scholar
  8. 8.
    G.H. Templeton, J.H. Mitchell and K. Wildenthal, Am. J. Physiol.222, 1406 (1972).PubMedGoogle Scholar
  9. 9.
    P.J. Bentley, O.A. Candia, M. Parisi and A.J. Saladino, Am. J. Physiol.225, 818 (1973).PubMedGoogle Scholar
  10. 10.
    E. Bozler, Am. J. Physiol.200, 656 (1961).Google Scholar
  11. 11.
    E.D. Frohlich, Archs int. Pharmacodyn. Ther.161, 154 (1966).Google Scholar
  12. 12.
    J. Koch-Weser, Am. J. Physiol.204, 957 (1963).PubMedGoogle Scholar
  13. 13.
    E. Page and R.S. Bernstein, J. gen. Physiol.47, 1129 (1964).PubMedGoogle Scholar

Copyright information

© Birkhäuser Verlag 1978

Authors and Affiliations

  • G. Pogátsa
    • 1
  • E. Dubecz
    • 1
  1. 1.Research UnitNational Institute of CardiologyBudapest(Hungary)

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