Skip to main content
SpringerLink
Log in

The effects of brain monoamine depletion on p-chlorophenyl-alanine-induced hypothermia

  • Physiologica
  • Published:
Experientia Aims and scope Submit manuscript

    We’re sorry, something doesn't seem to be working properly.

    Please try refreshing the page. If that doesn't work, please contact support so we can address the problem.

Summary

I.p. administration of p-chlorophenylalanine produced a fall in rectal temperature in rats. The hypothermia was attenuated after pretreatment of the animals with 5,6-dihydroxytryptamine, but was unaffected after pretreatment of the animals with 6-hydroxydopamine.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. A.H. Amin, T.B.B. Crawford and J.H. Gaddum, J. Physiol. (Lond.)126, 596 (1954).

    Article  CAS  PubMed  Google Scholar 

  2. R.F. Hellon, Pharmac. Rev.26, 289 (1975).

    CAS  Google Scholar 

  3. N.J. Giarman, C. Tanaka, J. Mooney and E. Atkins, Adv. Pharmac.64A, 307 (1968).

    Article  Google Scholar 

  4. K. Koe and A. Weissman, J. Pharmac. exp. Ther.154, 499 (1966).

    CAS  Google Scholar 

  5. A.R. Somerville and B.A. Whittle, Br. J. Pharmac.31, 120 (1967).

    CAS  Google Scholar 

  6. M.T. Lin, W.Y. Chia, C.T. Tsai and T.H. Yin, Experientia34, 756 (1978).

    Article  CAS  PubMed  Google Scholar 

  7. H.G. Baumgarten, H.G., A. Bjorklund, A. Holstein and A. Nobin, Z. Zellforsch.129, 256 (1972).

    Article  CAS  PubMed  Google Scholar 

  8. A. Bjorklund, A. Nobin and U. Stenevi, Brain Res.53, 117 (1973).

    Article  CAS  PubMed  Google Scholar 

  9. J.G.V. Zoeren and E.M. Stricker, Am. J. Physiol.230, 932 (1976).

    Article  PubMed  Google Scholar 

  10. M.T. Lin and J.T. Stitt, Physiologist19, 271 (1976).

    Google Scholar 

  11. M.T. Lin, J. Pharmac. exp. Ther.204, 39 (1978).

    CAS  Google Scholar 

  12. C. Atack and M. Lindqvist, Naunyn-Schmiedebergs Arch. Pharmac.279, 267 (1973).

    Article  CAS  Google Scholar 

  13. W. Feldberg and V.J. Lotti, Br. J. Pharmac.31, 152 (1967).

    CAS  Google Scholar 

  14. R.D. Myers and T.L. Yaksh, Physiol. Behav.3, 917 (1968).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Physiology and Biophysics, National Defense Medical Center, Taipei, Taiwan

    M. T. Lin, Y. F. Chern & S. I. Chern

Authors
  1. M. T. Lin
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Y. F. Chern
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. S. I. Chern
    View author publications

    You can also search for this author in PubMed Google Scholar

Additional information

This work was supported by grants from the National Science Council (Republic of China) and J. Aron Charitable Foundation (USA). The authors are grateful to Dr C.Y. Chai, Dr T.H. Yin, Dr H.H. Lu and Mr C.C. Wei for their advice and support.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Lin, M.T., Chern, Y.F. & Chern, S.I. The effects of brain monoamine depletion on p-chlorophenyl-alanine-induced hypothermia. Experientia 34, 1595–1596 (1978). https://doi.org/10.1007/BF02034695

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02034695

Keywords

Search

Navigation