Summary
Phenylketonuric squirrels have shown marked inhibition of alkaline phosphatatase in the olfactory lobes and cerebral hemispheres, whereas the Na+-K+-ATPase remained less altered. In the pathogenesis of phenylketonuria inhibition of alkaline phosphatase at the level of ‘Blood-Brain Barrier’ (BBB), leads transport system to impaired functioning.
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This work was done in the Department of Zoology, University of Udaipur, Udaipur-313001, India.
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Bhatt, D.K. Imbalance in the activities of alkaline phosphatase and Na+-K+-ATPase in the brain of experimentally induced phenylketonuric squirrels (Funambulus palmarum). Experientia 34, 1549–1550 (1978). https://doi.org/10.1007/BF02034665
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DOI: https://doi.org/10.1007/BF02034665