To study the effect of a combined HeNe and i.r. laser treatment on the regeneration of the lymphatic system during the process of wound healing, we compared the evolution of a surgical induced incision wound in two groups of mice.
In the control group (N=500) as well as in the test group (N=100) we studied the evolution of four parameters (adhesion, local oedema, regeneration of the vein and regeneration of the lymph vessel) by means of microscopic observations using a cold light source to illuminate the everted skin of the mice. The wounds in the test group were irradiated twice a day with a combined HeNe and i.r. laser. The adhesion of the scar with the underlying tissues disappeared after 10 days in the control group and after 4 days in the test group. The local oedema disappeared in the test group after 8 days while in the control group it lasted until 10 days. A considerable acceleration of the regeneration of both vein and lymph vessel was seen in the test group.
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Lievens, P.C. The effect of a combined HeNe and i.r. laser treatment on the regeneration of the lymphatic system during the process of wound healing. Laser Med Sci 6, 193–199 (1991). https://doi.org/10.1007/BF02032548