Low-power laser therapy in rheumatoid arthritis
Thirty-five patients suffering from rheumatoid arthritis were allocated at random to treatment with either a low-power laser (3.58 J cm−2, continuous wave 820 nm) or a placebo in a 4-week, double-blind study. Eight finger joints (2nd–5th metacarpo- and proximal interphalangeal joints) of the most affected hand were treated. In the laser group the grip strength and finger flexibility improved, the swelling of the joints declined, the morning stiffness and pain decreased. The sedimentation rate and the number of leukocytes showed a fall with a significant trend. In the placebo group there were no changes in these parameters except for the registration of pain, where a significant, less than with the laser, effect was observed. Thus, low-power laser therapy, at the chosen wavelength and energy dose, appears to be effective against the classical complaints from rheumatoid arthritis.
Key wordsLow-power laser Rheumatoid arthritis
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- 1.Masi AT, Medsger TA. Epidemiology of the rheumatic diseases. In: McCarthy DJ (ed)Arthritis and Allied Conditions. Philadelphia: Lea and Fibiger 1979:11–35Google Scholar
- 2.Bliddal H, Hellesen C, Ditlevsen P et al. Soft-laser therapy of rheumatoid arthritis.Scand J Rheumatology 1987,16:225–8Google Scholar
- 3.Goldman JA, Chiapella J, Casey H et al. Laser therapy of rheumatoid arthritis.Laser Surg Med 1980:93–102Google Scholar
- 6.Steinbrocker O, Traeger C, Battermann RC. Therapeutic criteria in rheumatoid arthritis.JAMA 1949,140:659Google Scholar
- 7.Huskisson EC. Assessment for clinical trials.Clinics Rheum Dis 1976,2:37–49Google Scholar
- 8.Huskisson EC. The drug treatment of osteoarthritis.Scand J Rheumatology (Suppl) 1980,43:57–61Google Scholar
- 10.Wright V. The management of degenerative joint disease.Scand J Rheumatol (Suppl) 1980,43:7–11Google Scholar
- 11.Bolagni L, Daviolo E, Volpi N. Effects of GaAs pulsed Laser on ATP concentration and ATPase activity in vitro and in vivo. In: Galleti G (ed)Laser. Proceedings of the International Congress on Laser in Medicine and Surgery. Bologna: Monduzzi Editore 1985:47–51Google Scholar
- 13.Karu TI, Lukpanova GG, Parkhomenko IH, Chirkov YY. Changes in cAMP level in mammalian cells after irradiation with monochromatic visible light.Proc USSR Acad Sci, Biophys 1985,281:1242–4Google Scholar
- 14.Antikas T. Effect of low power laser irradiation on macrophage population models in vitro. Abstract inInternational congress in Laser Therapy III. Brussels, October 1987:17–18Google Scholar