Summary
Two cases of beta thalassaemia with pseudoxanthoma elasticum and angioid streaks (Grönblad-Strandberg syndrome) are reported. To the best of our knowledge, this is the first report of a combination between these two genetically determined disorders. The possible theories of the pathogenesis of pseudoxanthoma elasticum and angioid streaks are discussed.
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Paton, D. The relation of angioid streaks to systemic disease. Springfield-Thomas 1972, 11–32.
Gibson, J.M., Chanduri, P.R., Rosenthal, A.R. Angioid streaks in a case of beta thalassaemia major. Br J Ophthalmol 1983, 67, 29–31.
Lippman, S.M., Abergel, R.P., Ginzton, L.E. et al. Mitral valve prolapse in Sickle Cell disease: Manifestation of a generalised connective tissue disorder. Am J. Hematol 1985, 19, 1–12.
Terry, T.L. Angioid streaks and osteitis deformans. Transactions of the Am J Ophthalm Soc 1934, 32, 555.
Nagpal, K.C., Asdourian, G., Goldbaum, M., Apple, D., Goldberg, M.F. Angioid streaks and sickle haemoglobinopathies. Br J Ophthalmol 1976, 60, 31–34.
Condon, P.I., Serjeant, G.R. Ocular findings in elderly cases of homozygous sickle cell disease in Jamaica. Br J Ophthalmol 1976, 60, 361–4.
Singerman, L.J., Hatem, G. Laser treatment of choroidal neovascular membranes in angioid streaks. Retina 1981, 1, 75–83.
Theodossiadis, G., Ladas, I., Koutsandrea, C., Damanakis, A., Petroutsos, G. Thalassemie en neovaisseaux sous-retiniens maculaires. J Fr Ophthalmol 1984, 7, 2, 115–8.
Nickoloff, B.J., Noodleman, F.R., Abel, E.A. Perforating pseudoxanthoma elasticum associated with chronic renal failure and hemodialysis. Arch Dermatol 1985, 121, 1321–1322.
Huerre, C., Junien, C., Weil, D., Chu, M.L. et al. Human type I procollagen genes are located on different chromosomes. Proc Natl Acad Sci USA 1982, 79, 6627–6630.
Sandberg, L.B., Davidson, J.M. Elastin and its gene. Peptide Prot Rev 1985, 1, 9, 1–12.
Hagedoorn, A. Angioid streaks. Arch Ophthalmol 1939, 21, 746, 935.
Hamilton, A.M., Pope, F.M., Condon, P.I. et al. Angioid streaks in Jamaican patients with homozygous sickle cell disease. Br J Ophthalmol 1981, 65, 341–7.
Singerman, L.J. Angioid streaks in thalassaemia. Br J Ophthalmol 1983, 67, 558.
Singerman, L.J. Angioid streaks associated with hereditary spherocytosis. Am J Ophthalmol 1984, 98, 647–8.1.
Peters, T.J., Seiden, C., Seymour, C.A. Lysosomal disruption in the pathogenesis of hepatic damage in primary and secondary hemochromatosis. In: Iron Metabolism. Ciba Foundation Symposium 1976, 51, 317–25.
Iancu, T.L., Neustein, H.B. Ferritin in human liver cell of homozygousβ-thalassemia: ultrastructural observations. Br J Haematol 1977, 37, 527–535.
Ley, T.J., Griffith, P., Nienhuis, A.W. Transfusion haemosiderosis and chelation therapy. In: Disorders of Iron Metabolism. Clin Haematol. 1982, 11, 2, 437–64.
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Aesopos, A., Stamatelos, G., Savvides, P. et al. Pseudoxanthoma elasticum and angioid streaks in two cases ofβ-thalassaemia. Clin Rheumatol 8, 522–527 (1989). https://doi.org/10.1007/BF02032108
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DOI: https://doi.org/10.1007/BF02032108