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Clinical Rheumatology

, Volume 2, Issue 1, pp 13–17 | Cite as

Spontaneous nasal septal perforation in patients with rheumatoid arthritis

  • J. L. Mathews
  • J. R. Ward
  • C. O. Samuelson
  • W. P. Knibbe
Originals

Summary

Nasal septal perforation is known to be associated with various traumatic and disease states, yet spontaneous nasal septal perforation (SNSP) is relatively rare. SNSP has been reported in three patients with seropositive rheumatoid arthritis (RA) and we report an additional seven patients with SNSP and RA, four of whom were seronegative and none of whom had Raynaud's, in contrast to those reported previously. Manifestations of overt infectious, neoplastic or granulomatous disease have not been found in our seven patients over several years of close follow-up. We have identified no obvious pathogenesis or specific etiology for SNSP. We suggest that SNSP may represent an unusual manifestation of RA previously not well recognized.

Key words

Rheumatoid Arthritis Spontaneous Nasal Septal Perforation 

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Copyright information

© Springer-Verlag 1983

Authors and Affiliations

  • J. L. Mathews
    • 1
  • J. R. Ward
    • 1
  • C. O. Samuelson
    • 1
  • W. P. Knibbe
    • 1
  1. 1.Department of Internal Medicine, Division of RheumatologyUniversity of Utah Medical CenterSalt Lake CityUSA

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