Infectious involvements in males with Reiter's syndrome
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To obtain data on infectious involvements contributing to joint attacks in Reiter's syndrome (RS) 72 consecutive males with RS were investigated. Controls were 219 personally interviewed males. A history of some type of oronaso-pharyngeal or pulmonary infectious involvements were reported as often in the patients as in the controls, but the frequency of persons with a history of joint manifestations followed by these infections was significantly higher in the patients (23/72) than in the controls (8/219) (p<0.0001). Gastrointestinal involvements occurred only in a minority of cases as a triggering infection. Histories of prostatitis, gonorrhoea, condylomata acuminata, haematuria and trichomonas vaginalis infections were significantly more common in patients than in controls (p < 0.001 − p < 0.025). This finding, as well as evidence of chlamydial infection in 61%, speaks in favour of the importance of sexually transmitted diseases as an etiologic agent. A case report of triggering infections during the course of RS is given and the possible role of these infections in the immunopathogenesis in RS is discussed.
Key wordsReiter's Syndrome Chlamydia Trachomatis Yersinia
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- 10.Leirisalo M. Rheumatic fever. Ann Clin Res, (suppl. 20) 1977, 9, 1–72.Google Scholar
- 11.Kousa, M. Clinical observations on Reiter's disease with special reference to the venereal and non-venereal aetiology. Acta Derm Venereol, (Suppl)(Stockh) 1978, 58, 1–36.Google Scholar
- 14.Schachter, J., Dawson, C.R. Human chlamydial infections. Littleton, Massachusetts, PSG Publishing Company, 1978.Google Scholar
- 15.Leino, R. Human yersiniosis. A clinical study with special reference to lymphocyte transformation in Yersinia arthritis. Academic dissertation, University of Turku, Turku Finland 1982.Google Scholar
- 18.Vuento, R., Leino, R., Viander, M., Toivanen, A. In vitro lymphoproliferative response to Yersinia: depressed response in arthritic patients years after Yersinia infection. Clin Exp Rheum, 1983, 1, 219–224.Google Scholar