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Osteoarticular manifestations in sickle-cell disorders

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Summary

The osteoarticular manifestations of the main sickling disorders (homozygous sickle cell-HbSS anaemia-, double heterozygous-HbS-β thalassaemia, double heterozygous HbS-C disease and sickle cell-trait) are reviewed; They may be grouped into 3 main categories: vaso-occlusive, infective and metabolic. The pathophysiology and pathogenesis as well as the treatment are discussed.

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  1. First Department of Internal Medicine, University of Athens, School of Medicine, Laikon General Hospital, 17, Aghiou Thoma (Goudi), 115 27, Athens, Greece

    Phaedon Kaklamanis

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Kaklamanis, P. Osteoarticular manifestations in sickle-cell disorders. Clin Rheumatol 3, 419–434 (1984). https://doi.org/10.1007/BF02031264

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