Summary
Bone affectation in systemic lupus erythematosus (SLE) is caused both by the disease itself and by the treatment used. We report the case of a woman diagnosed of SLE, who, in the course of her illness, develops multiple aseptic osteonecrosis (AON) and laminar periostitis, radiologically compatible with the diagnosis of hypertrophic osteoarthropathy (HOA), with no evidence of acropaquia. In this case, the patient shows all the risk factors involved in the pathogenesis of the development of ischemia in bone microcirculation.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Zizic, T., Hungerford, D., Stevens, M.B. Ischemic bone necrosis in systemic lupus erythematosus. Medicine (Baltimore) 1980, 59, 134–142.
Hungerford, D., Zizic, T. The treatment of ischemic necrosis of bone in systemic lupus erythematosus. Medicine (Baltimore) 1980, 59, 143–148.
Smith, E.E., Sweet, D.E. Brunner, C.M. Davis, J.S. Avascular necrosis in SLE: an apparent predilection for young patients. Ann Rheum Dis 1976, 35, 227–232.
Kallas, A.A., Learmonth, I.D., Klemp, P. Early treatment of avascular necrosis in systemic lupus erythematosus. Ann Rheum Dis 1986, 45, 649–652.
Resnick, D., Niwayama, G. Diagnosis of bone and joint disorders. Ed. Saunders. Philadelphia. 1988, 96, 4073–4139.
Tan, E.M., Cohen, A.S., Fries, J.F. et al. The revised criteria for the classification of systemic lupus erythematosus. Arithritis Rheum 1983, 25, 1271–1277.
Dubois, E.L., Cozen, L. Avascular bone necrosis associated with SLE. JAMA 1960, 174, 966–971.
Asherson, R.A., Jungers, P., Liote, F. et al. Ischemic necrosis of bone associated with the “lupus anticoagulant” and antibodies to cardiolipin. Preceding of XVIth International Congress of Rheumatology. Sydney, Australia 1983, 373.
Cruess, R.L. Steroid-induced osteonecrosis: a review. Can J Surg 1981, 24, 567–571.
Ruderman, M., MacCarty, D.J. Aseptic necrosis in systemic lupus erythematosus. Report of a case involving six joints. Arthritis Rheum 1964, 7, 709–721.
Darlington, L.G. Osteonecrosis at multiple sites in a patient with systemic lupus erythematosus. Ann Rheum Dis 1985, 44, 65–66.
Hungerford, D. Pathogenetic considerations in ischaemic necrosis of bone. Can J Surg 1981, 24, 583–588.
Fisher, D., Bickel, W. Corticosteroid induced AVN. J Bone Joint Surg 1971, 53A, 859–873.
Jaffe, W., Epstein, M., Heyman, N., Mankin, H. The effect of cortisona on femoral and humeral heads in rabbits. Clin Orthop 1972, 82, 221–228.
King, J. Localized clubbing and hypertrophic osteoartropathy due to infection in an aortic prosthesis. Br J Med 1972, 4, 404.
Canalis, E. Hipocratismo digital y osteoartropatia hipertrofica. Definicion y etiopatogenia. Med Clin (Barc) 1986, 86, 647–653.
Glickstein, M., Neustadter, L., Dalinka, M., Kricun, M. Periosteal reaction in systemic lupus erythematosus. Skeletal Radiol 1986, 15, 610–612.
Mackie, R. Lupus erythematosus in association with finger-clubbing. Br J Dermatol 1973, 89, 533–535.
Meijers, A., Pasé, D., Loose, H. et al. Periarteritis nodosa and subperiosteal new bone formation. J Bone Joint Surg 1982, 64B, 592–596.
Leskinen, R.H. Skrifvars, B.V., Laasonen, L.S., Edgren, K.J. Bone lesions in systemic lupus erythematosus. Radiology 1984, 153, 349–352.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Burson, J.S., Graña, J., Varela, J. et al. Laminar periostitis and multiple osteonecrosis in systemic lupus erythematosus. Clin Rheumatol 9, 535–538 (1990). https://doi.org/10.1007/BF02030518
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF02030518