Skip to main content
SpringerLink
Log in

A fluorescein angiographic study on patients with proliferative vitreoretinopathy treated by vitrectomy and intraocular daunomycin

  • Published:
International Ophthalmology Aims and scope Submit manuscript

Abstract

Fluorescein angiographic findings in patients with proliferative vitreoretinopathy treated by victrectomy, silicone oil tamponade and intraocular daunomycin are compared to findings in patients who received the same treatment but no intraocular drug. A difference between drug treated and untreated eyes was not discovered. We observed, however, a delayed arteriovenous passage time, cystoid macular edema, ectopia of the foveolar region and late hyperfluorescence of the optic disk; these findings might partly explain the visual results. Reduction of redetachment and thus prevention of reoperations by treatment with anti-proliferative drugs may decrease the rate of cystoid macular edema and thus improve the functional results of surgical treatment.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Ando F. Intraocular hypertension resulting from pupillary block by silicone oil. Am J Ophthalmol 1985; 99: 87–8.

    PubMed  Google Scholar 

  2. Bonnet M. Prognosis of cystoid macular edema after retinal detachment repair. Graefe's Arch Clin Exp Ophthalmol 1986; 224: 13–7.

    Google Scholar 

  3. Bonnet M, Bievelez B, Noel A, Bensoussan B, Pignault C. Fluorescein angiography after retinal detachment microsurgery. Graefe's Arch Clin Exp Ophthalmol 1983; 221: 35–40.

    Google Scholar 

  4. Lobes LA, Grand MG. Incidence of cystoid macular edema following scleral buckling procedure. Arch Ophthalmol 1980; 98: 1230–2.

    PubMed  Google Scholar 

  5. Piccolino FC. Vascular changes in rhegmatogenous retinal detachment. Ophthalmologica Basel 1983; 186: 17–24.

    Google Scholar 

  6. Santana M, Wiedemann P, Kirmani M, Minckler DS. Patterson R, Sorgente N, Ryan SJ. Daunomycin in the treatment of experimental proliferative vitreoretinopathy: Retinal toxicity of intravitreal daunomycin in the rabbit. Graefe's Arch Clin Exp Ophthalmol 1984; 221: 210–3.

    Google Scholar 

  7. Schatz H, Burton TC, Yannuzzi LA, Rabb MF. Interpretation of fundus fluorescein angiography. Saint Louis: The C.V. Mosby Company, 1978; 546–9.

    Google Scholar 

  8. Wiedemann P. Die medikamentöse Behandlung der proliferativen Vitreoretinopathie unter besonderer Berücksichtigung des Zytostatikums Daunomycin. Stuttgart: Enke, 1988.

    Google Scholar 

  9. Wiedemann P, Lemmen K, Schmiedl R, Heimann K. Intraocular daunomycin for the treatment and prophylaxis of traumatic proliferative vitreoretinopathy. Am J Ophthalmol 1987; 104: 10–4.

    PubMed  Google Scholar 

Download references

Author information

Author notes

  1. P. Y. Evans

    Present address: Center for Sight, Georgetown University, Washington, D.C.

Authors and Affiliations

  1. Department of Vitreoretinal Surgery at the University Eye Clinic Cologne, Cologne, Germany

    P. Wiedemann,  P. Y. Evans, R. Wiedemann, R. Meyer-Schwickerath & K. Heimann (Direktor)

Authors
  1. P. Wiedemann
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. P. Y. Evans
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. R. Wiedemann
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. R. Meyer-Schwickerath
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. K. Heimann
    View author publications

    You can also search for this author in PubMed Google Scholar

Additional information

spent a sabbatical leave in our Department during 1985.

This paper is supported in part by the Retinovit Foundation and by the Forschungsförderung Nordrhein-Westfalen.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Wiedemann, P., Evans, P.Y., Wiedemann, R. et al. A fluorescein angiographic study on patients with proliferative vitreoretinopathy treated by vitrectomy and intraocular daunomycin. Int Ophthalmol 13, 211–216 (1989). https://doi.org/10.1007/BF02028213

Download citation

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02028213

Key words

Search

Navigation