N-cadherin detected in the membrane fraction of lens fiber cells
N-cadherin was identified as a glycoprotein present in the fiber cell membranes of frog, chick, bovine, rabbit and human lenses. The molecular size of N-cadherin varies with the species. Homogenization of the chick lens in the presence of Ca2+ resulted in a decrease in the concentration of N-cadherin. This suggests that the lens contains a Ca2+-activated protease which can act on N-cadherin.
Key wordsLens membranes, N-cadherin glycoproteins
- 1.Takeichi, M., Trends Genet.3 (1987) 213.Google Scholar