Summary
In rat embryo skeletal myotubes, acetylcholinesterase is present, as multiple forms, and can be detected in deposits at the cell surface. Myotubes cultured in the presence of β-endorphin, exhibit an increased predominance of the globular (precursor) forms of the enzyme, which are largely restricted to intracellular sites associated with nuclei. In the presence of β-endorphin-(1-27), the relative proportions of the different forms of acetylcholinesterase is similar to that seen in the controls, but the enzyme is intracellular and has a characteristic focal localisation in the myotube.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Rieger, F., Koenig, J., and Vigney, M., Devl Biol.76 (1980) 358.
Brockman, S. K., Younkin, L. H., and Younkin, S. G., J. Neurosci.4 (1984) 131.
Bulger, J. E., Randall, W. R., Nieberg, P. S., Patterson, G. T., McNamee, M. G., and Wilson, B. W., Dev. Neurosci.5 (1982) 474.
Fernandez, H. L., Patterson, M. R., and Duell, M. J., J. Neurobiol.11 (1980) 557.
Haynes, L. W., Smyth, D. G., and Zakarian, S., Brain Res.232 (1982) 115.
Haynes, L. W., and Smith, M. E., Neurosci Lett.55 (1985) 125.
Haynes, L. W., Smith, M. E., and Smyth, D. G., J. Neurochem.42 (1984) 1542.
El Badawi, A., and Schenk, E. A., J. Histochem. Cytochem.15 (1976) 580.
Inestrosa, N. C., Silberstein, L., and Hall, Z. W., Cell29 (1982) 71.
Kupfer, C., and Koelle, G. B., J. exp. Zool.116 (1951) 397.
Haynes, L. W., and Smith, M. E., J. Physiol. (Lond.)351 (1984) 22P.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Haynes, L.W., Smith, M.E. Localisation of acetylcholinesterase in rat myotubes in the presence of β-endorphin and β-endorphin-(1-27). Experientia 46, 211–213 (1990). https://doi.org/10.1007/BF02027318
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/BF02027318