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Metabolism in porifera IV. Biosynthesis of the 3β-Hydroxymethyl-A-nor-5α-Steranes from cholesterol byAxinella verrucosa

Riassunto

La spugnaAxinella verrucosa trasforma il [4-14C]-colesterolo nel 3β-idrossimetil-A-nor-5α-colestano (1), mentre utilizza 1′[1-14C]-acetato per la sintesi dei 3β-idrossimetil-A-nor-sterani (1–6) in misura trascurabile. Si suggerisce che questi unici stanoli si originino principalmente per modificazione di steroli dietarici. II carbonio-4 del nucleo del colesterolo non è nè perso nè dà origine al carbonio 3β-idrossimetilico dello scheletro A-nor-colestanico.

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De Rosa, M., Minale, L. & Sodano, G. Metabolism in porifera IV. Biosynthesis of the 3β-Hydroxymethyl-A-nor-5α-Steranes from cholesterol byAxinella verrucosa . Experientia 31, 408–410 (1975). https://doi.org/10.1007/BF02026345

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  • DOI: https://doi.org/10.1007/BF02026345

Keywords

  • Cholesterol
  • Acetato