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Dietary recommendations for coronary heart disease prevention: implications for non-cardiovascular diseases

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Summary

In order to reduce the lipoprotein-related risk of coronary heart disease, nutritional recommendations have been formulated for use by communities prone to atherosclerosis and its complications. As such recommendations are potentially of widespread application they require careful scrutiny to assess possible risks as well as benefits.

Epidemiological, clinical and experimental data concerning relationships between these nutrients and non-cardiovascular diseases are reviewed with emphasis on cancer mortality. Changes in intake of fats, including polyunsaturated fat, of cholesterol, carbohydrate, fibre, sodium and β-carotene are discussed, and evidence of a relationship between serum cholesterol concentration and cancer is examined. These considerations offer reasonable reassurance as to the safety of recent dietary recommendations for the reduction of coronary heart disease.

Zusammenfassung

Um das mit Lipoprotein verbundene Risiko von koronarer Herzerkrankung zu vermindern, sind Ernährungsempfehlungen für Populationen mit Empfänglichkeit für Atherosklerose und seine Komplikationen dargelegt worden. Da solche Empfehlungen möglicherweise weitverbreitet anzuwenden sind, müssen diese gründlich untersucht werden, um sowohl Risiken als auch Vorteile zu bestimmen.

Die vorliegende Arbeit bespricht epidemiologische, klinische und experimentelle Daten über Beziehungen zwischen diesen Nährstoffen und nichtkardiovaskulären Erkrankungen, mit Nachdruck auf Krebsmortalität. Veränderungen der Aufnahme von Fett (polyungesättigtes Fett mit eingeschlossen), Cholesterol, Kohlenhydraten, Natrium und β-Carotin werden diskutiert, und Beweise für eine Beziehung zwischen Serumcholesterol-Konzentration und Krebs werden geprüft. Es wird beschlossen, daß die jüngsten Ernährungsempfehlungen zur Verminderung von koronarer Herzerkrankung leidlich zuverlässig sind.

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  1. B. Lewis

    Present address: Department of Chemical Pathology and Metabolic Disorders, St. Thomas' Hospital, London, UK

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    Lewis, B. Dietary recommendations for coronary heart disease prevention: implications for non-cardiovascular diseases. Z Ernährungswiss 22, 147–156 (1983). https://doi.org/10.1007/BF02024690

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