Radiologic features of gastric outlet obstruction in infants after long-term prostaglandin administration
- 55 Downloads
Long-term prostaglandin (PG) therapy has recently been associated with gastric mucosal hyperplasia. We reviewed the clinical and radiologic (especially sonographic) records of eight patients with complex congenital heart disease who were on PG therapy. Feeding problems, vomiting, and abdominal distension were present in six patients. Barium meal revealed antral narrowing in three patients, suggestive of hypertrophic pyloric stenosis in two. Sonography showed a variable degree of increased gastric mucosal lobulation often accompanied by a marked polypoid or lobular appearance. Cortical hyperostosis related to PG therapy was seen in three patients. PG-associated gastric mucosal hyperplasia can cause feeding problems and pronounced gastric lobulation.
KeywordsHeart Disease Barium Prostaglandin Congenital Heart Disease Congenital Heart
Unable to display preview. Download preview PDF.
- 7.Classen M, Sturzenhofecker P, Koch H, Demling L (1973) The effect of prostaglandin E1 on the secretion and the motility of the human stomach. Acta hepatol Gastroenterol 20: 159–162Google Scholar