Pediatric Radiology

, Volume 25, Issue 1, pp 41–43 | Cite as

Radiologic features of gastric outlet obstruction in infants after long-term prostaglandin administration

  • P. Babyn
  • N. Peled
  • D. Manson
  • O. Dagan
  • M. M. Silver
  • G. Koren


Long-term prostaglandin (PG) therapy has recently been associated with gastric mucosal hyperplasia. We reviewed the clinical and radiologic (especially sonographic) records of eight patients with complex congenital heart disease who were on PG therapy. Feeding problems, vomiting, and abdominal distension were present in six patients. Barium meal revealed antral narrowing in three patients, suggestive of hypertrophic pyloric stenosis in two. Sonography showed a variable degree of increased gastric mucosal lobulation often accompanied by a marked polypoid or lobular appearance. Cortical hyperostosis related to PG therapy was seen in three patients. PG-associated gastric mucosal hyperplasia can cause feeding problems and pronounced gastric lobulation.


Heart Disease Barium Prostaglandin Congenital Heart Disease Congenital Heart 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer-Verlag 1995

Authors and Affiliations

  • P. Babyn
    • 1
  • N. Peled
    • 2
  • D. Manson
    • 1
  • O. Dagan
    • 3
  • M. M. Silver
    • 4
  • G. Koren
    • 5
  1. 1.Department of Diagnostic ImagingThe Hospital for Sick ChildrenTorontoCanada
  2. 2.Department of RadiologyHadassah UniversityJerusalemIsrael
  3. 3.Department of PediatricsKaplan HospitalRehovotIsrael
  4. 4.Department of PathologyThe Hospital for Sick ChildrenTorontoCanada
  5. 5.Department of PaediatricsThe Hospital for Sick ChildrenTorontoCanada

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