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Giant hypothalamic hamartoma: An unusual neonatal tumor

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Abstract

A case of neonatal manifestation of giant hypothalamic hamartoma is reported. It is suggested that hypothalamic hamartoma should be included in the list of neonatal intracerebral tumors. Magnetic resonance imaging appearance similar to that of normal gray matter on T1-weighted images and slightly hyperintense on T2-weighted images, without enhancement after gadolinium injection, is suggestive of the diagnosis.

Hypothalamic hamartomas are congenital malformations, consisting of disorganized mature neuronal elements in proportions similar to that of normal tissue [1]. They are clinically evidenced in infants ranging from 1 to 7 years of age [1–5]. This report describes a histologically proved giant hypothalamic hamartoma diagnosed in the neonatal period. Magnetic resonance imaging (MRI) is helpful to distinguish this congenital non-evolution malformation from more aggressive neonatal tumors.

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Authors and Affiliations

  1. Department of Radiology, Montreal General Hospital, McGill University, 1650, Cedar Av, H3G 1A4, Montreal, PQ, Canada

    L. Guibaud

  2. Department of Pediatric Radiology, Hôpital Debrousse, Université Claude-Bernard Lyon I, UFR Lyon Sud, 29 rue Soeur Bouvier, F-69322, Lyon Cedex 05, France

    V. Rode, J. -P. Pracros, P. Foray & V. A. Tran-Minh

  3. Department of Neuropathology, Hôpital Neurologique P. Wertheimer, Université Claude-Bernard Lyon I, UFR Alexis Carrel, 59 bd Pinel, F-69394, Lyon Cedex 03, France

    G. Saint-Pierre

Authors
  1. L. Guibaud
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  2. V. Rode
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  3. G. Saint-Pierre
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  4. J. -P. Pracros
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  5. P. Foray
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  6. V. A. Tran-Minh
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Guibaud, L., Rode, V., Saint-Pierre, G. et al. Giant hypothalamic hamartoma: An unusual neonatal tumor. Pediatr Radiol 25, 17–18 (1995). https://doi.org/10.1007/BF02020833

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  • DOI: https://doi.org/10.1007/BF02020833

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