Zusammenfassung
Im Verlauf einer über 8 Monate durchgeführten Studie wurden die Auswirkungen der Einnahme von Lebertran auf das Blutfettverteilungsmuster von 11 Versuchspersonen untersucht. Hauptziel der Studie war es, den Nachweis zu führen, daß regelmäßig eingenommene, in Fischöl enthaltene, hoch ungesättigte ω-3-Fettsäureanteile zu einer Senkung von Serum-Triglyzeriden und-cholesterin führen können. Die Resultate zeigten nach 6 Monaten einen deutlichen Abfall der Triglyzeride und Cholesterinwerte, ein Trend, der sich nach weiteren 2 Monaten Karenz fortsetzte. Die anüatherosklerotische und antithrombozytenaggregatorische Wirkung von Fischöl ist in zahlreichen Veröffentlichungen beschrieben worden.
Summary
In a research study performed over eight months with five female and six male subjects (age 35–67 years) the effect of cod liver oil on the lipoprotein composition in the blood was tested. The main goal was to prove that the regular administration of so-called highly unsaturated ω-3-fatty acid components in fish oil (4 g per day over six months) may lead to a reduction of triglyceride and total cholesterol values. Furthermore, any changes in HDL and LDL cholesterol fractions as well as the bleeding time were registered. The average values of all subjects showed an essential reduction of the triglyceride and cholesterol values. The control examination after 8 months even showed a continuous trend. The LDL fractions on an average remained unchanged. It can be taken for granted that the administration of unsaturated fatty acids in cod liver oil shows a successful therapeutic effect by the reduction of triglyceride and cholesterol values. The antiatherosclerotic and the anti-platelet aggregational effect of fish oil has been described in many publications.
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Burchard, H.U., Tischendorf, F.W. Die Auswirkungen der Einnahme von Lebertran auf den Blutfettspiegel, das Lipoproteinprofil und die Blutungszeit. Z Ernährungswiss 27, 222–228 (1988). https://doi.org/10.1007/BF02019510
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DOI: https://doi.org/10.1007/BF02019510