Annals of Vascular Surgery

, Volume 8, Issue 2, pp 172–178 | Cite as

Infusion methods for determination of peripheral resistance: Influence of infused medium and back pressure

  • Eric Wahlberg
  • Pal Dag Line
  • Par Olofsson
  • Jesper Swedenborg
Original Articles


It has been suggested that peripheral vascular resistance (PR), measured intraoperatively, can predict the outcome of infrainguinal reconstructions. There is, however, a great deal of variability in design and predictive value with this method, and it is prone to technical difficulties and possible errors. The present study evaluated the influence of the choice of infusion medium and the back pressure on PR as measured by the infusion technique. In a porcine model of experimentally induced stenosis, standard PR (calculated by the pressure difference across the stenosis and the Doppler volume flow) was compared with PR based on infusions of blood or saline solution. With blood as the infusion medium there was a significant correlation between the PR and the standard values (r = 0.795,p = 0.0005),whereas there was no correlation when saline solution was infused (r = 0.067,p = 0.345).Subtracting the back pressure resulted in a slight improvement in the correlations between standard PR and PR measured after infusion of blood but not saline solution. In summary, blood should be used as an infusion medium in methods of PR determination, but the influence of back pressure remains uncertain.


Public Health Infusion Method Saline Solution Vascular Resistance Pressure Difference 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    Ascer E, Veith FJ, Morin L, et al. Quantitative assessment of outflow resistance in lower extremity arterial reconstructions. J Surg Res 1984;37:8–15.CrossRefPubMedGoogle Scholar
  2. 2.
    Parvin SD, Evans DH, Bell PRF. Peripheral resistance measurement in the assessment of severe peripheral vascular disease. Br J Surg 1985;72:751–753.PubMedGoogle Scholar
  3. 3.
    Barner H, Kaminski D, Codd J, et al. Hemodynamics of autogenous femoropopliteal bypass. Arch Surg 1974;109:291–293.PubMedGoogle Scholar
  4. 4.
    Beard J, Scott D, Skidmore R, et al. Operative assessment of femorodistal bypass grafts using a new Doppler flowmeter. Br J Surg 1989;76:925–928.PubMedGoogle Scholar
  5. 5.
    Ascer E, Veith FJ. Outflow resistance measurements in infrainguinal bypass operations by injecting saline and measuring the integral of pressure. In Greenhalgh RM, ed. Diagnostic Techniques and Assessment Procedures in Vascular Surgery. New York: Grune & Stratton, 1985, pp 269–283.Google Scholar
  6. 6.
    Cooper GG, Austin C, Fitzsimmons E, et al. Outflow resistance and early occlusion of infrainguinal bypass grafts. Eur J Vasc Surg 1990;4:279–283.PubMedGoogle Scholar
  7. 7.
    Ascer E, White SA, Veith FJ, et al. Outflow resistance measurement during infrainguinal arterial reconstructions: A reliable predictor of limb salvage. Am J Surg 1987;154:185–188.CrossRefPubMedGoogle Scholar
  8. 8.
    Vos GA, Rauwerda JA, Broek TA, et al. The correlation of perioperative outflow resistance measurements with patency in 109 infrainguinal arterial reconstructions. Eur J Vasc Surg 1989;3:539–542.PubMedGoogle Scholar
  9. 9.
    Peterkin G, LaMorte W, Menzoian J. Runoff resistance and early graft failure in infrainguinal bypass surgery. Arch Surg 1988;123:1199–1201.PubMedGoogle Scholar
  10. 10.
    Björneberg J, Albert U, Mellander S. Resistance responses in proximal arterial vessels, arterioles and veins during reactive hyperemia in skeletal muscle and their underlying regulatory mechanisms. Acta Physiol Scand 1990;139:535–550.PubMedCrossRefGoogle Scholar
  11. 11.
    Cooper GG, Hood JM, Barros D'Sa ABB. The “isolated” popliteal segment: A comparative evaluation of its vascular resistance. Eur J Vasc Surg 1990;4:493–496.PubMedGoogle Scholar
  12. 12.
    Ascer E, Veith FJ, Lesser ML, et al. Collateral back pressure—is it a valid predictor of infrainguinal bypass graft patency. J Surg Res 1985;38:433–460.CrossRefGoogle Scholar
  13. 13.
    Ascer E, Veith FJ, White-Flores S, et al. Intraoperative outflow resistance as predictor of late patency of femoropopliteal arterial bypasses. J Vasc Surg 1987;5:820–827.CrossRefPubMedGoogle Scholar
  14. 14.
    Peterkin GA, Manabe S, LaMorte WW, et al. Evaluation of a proposed standard reporting system for preoperative angiograms in infrainguinal bypass procedures: Angiographic correlates of measured runoff resistance. J Vasc Surg 1988;7:379–385.CrossRefPubMedGoogle Scholar

Copyright information

© Annals of Vascular Surgery Inc. 1994

Authors and Affiliations

  • Eric Wahlberg
    • 1
    • 2
  • Pal Dag Line
    • 1
    • 2
  • Par Olofsson
    • 1
    • 2
  • Jesper Swedenborg
    • 1
    • 2
  1. 1.Department of SurgeryKarolinska Hospital (E.W., P.O., and J.S.)StockholmSweden
  2. 2.Department of SurgeryAker Hospital (P.D.L.)OsloNorway

Personalised recommendations